Rho/Rac guanine nucleotide exchange factor 2 ; Homo sapiens






220 Article(s)
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1 1772451 Re-evaluation of rate constants involved in the action of the initiation and elongation factors eIF-2B and EF-Ts. Biochem Int 1991 Sep 2
2 2138201 A method to generate antigen-specific suppressor T cells in vitro from peripheral blood T cells of honey bee venom-sensitive, allergic patients. J Immunol Methods 1990 Mar 9 1
3 2229078 Purification and characterization of sea urchin initiation factor 2. The requirement of guanine nucleotide exchange factor for the release of eukaryotic polypeptide chain initiation factor 2-bound GDP. J Biol Chem 1990 Nov 5 2
4 2480379 Relationship between T cell receptors and antigen-binding factors. II. Common antigenic determinants and epitope recognition shared by T cell receptors and antigen-binding factors. J Immunol 1989 Dec 15 1
5 3377809 The effect of ethanol on polypeptide chain initiation in reticulocyte lysates. Inhibition of recycling of initiation factor eIF-2. Biochem Pharmacol 1988 May 15 3
6 3432064 [Evaluation of adriamycin cardiotoxicity using equilibrium radionuclide ventriculography. I. Results at rest]. Nuklearmedizin 1987 Oct 1
7 3462720 Formation of a translational inhibitor by interaction of phospholipid with the eukaryotic initiation factor 2. Proc Natl Acad Sci U S A 1986 Sep 3
8 3947361 Purification and properties of the guanine nucleotide exchange factor (GEF) from HeLa cells and its role in the initiation of protein synthesis. Biochem Biophys Res Commun 1986 Feb 13 6
9 6320181 Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2. Proc Natl Acad Sci U S A 1984 Jan 31
10 7581745 Translational control of eukaryotic gene expression. Role of the guanine nucleotide exchange factor and chain initiation factor-2. Enzyme Protein 1994-1995 6
11 8049218 Phosphorylation of the guanine nucleotide exchange factor and eukaryotic initiation factor 2 by casein kinase II regulates guanine nucleotide binding and GDP/GTP exchange. Biochemistry 1994 Aug 9 11
12 8589075 Small G proteins and the neutrophil NADPH oxidase. Biochimie 1995 1
13 8756332 Ras/Rap effector specificity determined by charge reversal. Nat Struct Biol 1996 Aug 1
14 9132016 Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation. Biochemistry 1997 Mar 25 2
15 9763446 Identification of regulators for Ypt1 GTPase nucleotide cycling. Mol Biol Cell 1998 Oct 2
16 9790530 Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell 1998 Oct 16 1
17 9843686 Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI). Curr Biol 1998 Dec 3 3
18 9857026 Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases. J Biol Chem 1998 Dec 25 3
19 10579920 Ras and Rap1: two highly related small GTPases with distinct function. Exp Cell Res 1999 Nov 25 2
20 10652228 Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. Biochem Biophys Res Commun 2000 Feb 5 2
21 10681520 Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src. J Biol Chem 2000 Feb 25 2
22 10748097 Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway. J Biol Chem 2000 May 26 1
23 10843989 The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins. J Biol Chem 2000 Aug 18 10
24 10934226 The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity. J Exp Med 2000 Aug 7 1
25 11085924 Identification and characterization of a novel Rho-specific guanine nucleotide exchange factor. Biochem J 2000 Dec 1 1
26 11087745 Phospholipase Cdelta1 is a guanine nucleotide exchanging factor for transglutaminase II (Galpha h) and promotes alpha 1B-adrenoreceptor-mediated GTP binding and intracellular calcium release. J Biol Chem 2001 Feb 23 3
27 11158328 New signaling pathways for hormones and cyclic adenosine 3',5'-monophosphate action in endocrine cells. Mol Endocrinol 2001 Feb 4
28 11248252 The Ras GDP/GTP cycle is regulated by oxidizing agents at the level of Ras regulators and effectors. FEBS Lett 2001 Mar 9 1
29 11278560 Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain. J Biol Chem 2001 Jun 1 4
30 11577097 Quantitative analysis of the effect of phosphoinositide interactions on the function of Dbl family proteins. J Biol Chem 2001 Dec 7 1
31 11595749 Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J Biol Chem 2001 Dec 14 22
32 11886862 Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase. J Biol Chem 2002 May 24 8
33 11896053 Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent. J Biol Chem 2002 May 24 1
34 11955434 P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell 2002 Mar 22 1
35 12475976 The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes". J Biol Chem 2003 Feb 14 1
36 12641750 Regulation of neuritogenesis and synaptic transmission by msec7-1, a guanine nucleotide exchange factor, in cultured Aplysia neurons. J Neurochem 2003 Apr 1
37 12680752 Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling. Biochemistry 2003 Apr 15 2
38 14597635 Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant. J Biol Chem 2004 Jan 30 4
39 14625275 Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase. J Biol Chem 2004 Feb 6 2
40 14654833 Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor. Nature 2003 Dec 4 1
41 14690595 Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism. Mol Cell 2003 Dec 2
42 14712228 Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential. Oncogene 2004 Jan 8 1
43 14970201 p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor. J Biol Chem 2004 Apr 30 2
44 15062102 Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol 2004 Apr 6 1
45 15319437 Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors. J Biol Chem 2004 Nov 5 1
46 15485841 Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. J Biol Chem 2005 Feb 11 1
47 15530360 The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle. Structure 2004 Nov 1
48 15544329 Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains. Biochemistry 2004 Nov 23 4
49 15616190 Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi. Mol Biol Cell 2005 Mar 2
50 15709769 Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model. Biochemistry 2005 Feb 22 9