CPRiL

OAS1

2'-5'-oligoadenylate synthetase 1

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, May 2022]

• 2'-5'-oligoadenylate synthase 1
• (2-5')oligo(A) synthase 1
• 2',5'-oligo A synthetase 1
2'-5'-oligoadenylate synthase 1 isoform p42
2'-5'-oligoadenylate synthetase 1, 40/46kDa
2'-5'-oligoisoadenylate synthetase 1
2-5A synthase 1
2-5A synthetase 1
E16 (2'-5') oligo A synthetase
E18/E16
IFI-4
IMD100
OIAS
OIASI