2'-5'-oligoadenylate synthetase 1 ; Homo sapiens






31 Article(s)
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1 14728690 Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1. Eur J Biochem 2004 Feb 1
2 16014697 Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype? J Med Genet 2006 Feb 2
3 18421422 Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: effects of 17beta-estradiol on the regulation of OAS1g in both tissues. Mol Cell Biochem 2008 Jul 1
4 19462904 [The correlation of myxovirus resistance 1 and 2'5'-ollgoadenylate synthetase 1 with clinical features of systemic lupus erythematosus]. Sichuan Da Xue Xue Bao Yi Xue Ban 2009 Mar 1
5 21145800 IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy. J Hepatol 2011 Jun 1
6 22752226 Genetic variation that predicts platinum sensitivity reveals the role of miR-193b* in chemotherapeutic susceptibility. Mol Cancer Ther 2012 Sep 1
7 23110939 Type I IFN receptor controls activated TYK2 in the nucleus: implications for EAE therapy. J Neuroimmunol 2013 Jan 15 2
8 23319625 Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A 2013 Jan 29 4
9 23401273 Immune activation of human brain microvascular endothelial cells inhibits HIV replication in macrophages. Blood 2013 Apr 11 1
10 23575436 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population. J Hum Genet 2013 Jun 1
11 25205466 Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism. BMC Cell Biol 2014 Sep 9 2
12 25450683 Anti-interferon-α neutralizing antibody induced telaprevir resistance under the interferon-α plus telaprevir treatment in vitro. Biochem Biophys Res Commun 2014 Nov 21 1
13 25477390 A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1. Nucleic Acids Res 2015 Jan 5
14 25517543 Rapid Uptake and Inhibition of Viral Propagation by Extracellular OAS1. J Interferon Cytokine Res 2015 May 3
15 25892109 The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity. Structure 2015 May 5 1
16 26516113 Low expression of microRNA-21 contributes to LPS-induced osteoblast cell apoptosis through up-regulation of OAS1. Cell Mol Biol (Noisy-le-grand) 2015 Oct 23 5
17 26997919 A Modified Coupled Spectrophotometric Method to Detect 2-5 Oligoadenylate Synthetase Activity in Prostate Cell Lines. Biol Proced Online 2016 1
18 30078389 OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages. BMB Rep 2019 Feb 1
19 30713099 Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates. Cell Host Microbe 2019 Feb 13 2
20 30814222 OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug. Proc Natl Acad Sci U S A 2019 Mar 12 4
21 31154625 Involvement of Interferon Regulatory Factor 7 in Nicotine's Suppression of Antiviral Immune Responses. J Neuroimmune Pharmacol 2019 Dec 2
22 31209803 Inhibition of PARP1 Increases IRF-dependent Gene Transcription in Jurkat Cells. Curr Med Sci 2019 Jun 2
23 32013110 Characteristics of Human OAS1 Isoform Proteins. Viruses 2020 Jan 29 1
24 32323871 Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death. EMBO J 2020 Jun 2 4
25 32413313 Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2. Biophys J 2020 Jun 2 1
26 32678884 Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs. Nucleic Acids Res 2020 Jul 27 6
27 33405993 Safety, pharmacokinetics and pharmacodynamics of TQ-A3334, an oral toll-like receptor 7 agonist in healthy individuals. Expert Opin Investig Drugs 2021 Mar 1
28 33922087 Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes. Biomolecules 2021 Apr 22 4
29 34411225 RARγ activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway. Blood 2022 Jan 6 1
30 34731560 Corylin sensitizes breast cancer cells to overcome tamoxifen resistance by regulating OAS1/miR-22-3p/SIRT1 axis. Acta Biochim Pol 2021 Nov 3 10
31 35220042 Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis. EBioMedicine 2022 Mar 2