| Protein Name | dopamine receptor D4 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1815 |
| Gene Symbol | DRD4 |
| UniProt | P21917 (DRD4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
239
Total Number of Articles : 373 |
Description |
dopamine receptor D4 |
| Gene Summary |
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008] |
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