Protein Name dopamine receptor D4
Organism Homo sapiens
Gene ID 1815
Gene Symbol


UniProt P21917 (DRD4_HUMAN)
Relationships Total Number of functionally related compound(s) : 239
Total Number of Articles : 373

dopamine receptor D4

Gene Summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]

  • D(4) dopamine receptor
  • D(2C) dopamine receptor
  • dopamine D4 receptor
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