Protein Name fibroblast growth factor 21
Organism Mus musculus
Gene ID 56636
Gene Symbol

Fgf21

UniProt Q9JJN1 (FGF21_MOUSE)
Relationships Total Number of functionally related compound(s) : 250
Total Number of Articles : 439
Description

fibroblast growth factor 21

Gene Summary

Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; cerebellum; integumental system; limb; and skeleton. Orthologous to human FGF21 (fibroblast growth factor 21). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • fibroblast growth factor 21
  • fibroblast growth factor 8c
  • Fgf8c
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Properties