Protein Name potassium inwardly rectifying channel subfamily J member 5
Organism Homo sapiens
Gene ID 3762
Gene Symbol

KCNJ5

UniProt P48544 (KCNJ5_HUMAN), A0A5J6E2W8 (A0A5J6E2W8_HUMAN)
Relationships Total Number of functionally related compound(s) : 88
Total Number of Articles : 144
Description

potassium inwardly rectifying channel subfamily J member 5

Gene Summary

This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]

synonyms
  • G protein-activated inward rectifier potassium channel 4
  • IRK-4
  • cardiac ATP-sensitive potassium channel
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Properties