Protein Name runt related transcription factor 2
Organism Mus musculus
Gene ID 12393
Gene Symbol


UniProt Q08775 (RUNX2_MOUSE), F8WHN7 (F8WHN7_MOUSE), E0CZ12 (E0CZ12_MOUSE), Q9Z2T9 (Q9Z2T9_MOUSE)
Relationships Total Number of functionally related compound(s) : 431
Total Number of Articles : 528

runt related transcription factor 2

Gene Summary

This gene encodes a member of the runt domain-containing family of transcription factors. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Sep 2015]

  • runt-related transcription factor 2
  • AKV core binding factor
  • PEA2-alpha A
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