runt related transcription factor 2 ; Mus musculus






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1 8995235 1,25-dihydroxyvitamin D3 inhibits Osteocalcin expression in mouse through an indirect mechanism. J Biol Chem 1997 Jan 3 1
2 9830051 Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. J Biol Chem 1998 Dec 4 3
3 9837769 Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF). Biochem Biophys Res Commun 1998 Nov 27 3
4 10521447 AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene. J Biol Chem 1999 Oct 22 2
5 10597314 A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc. Oncogene 1999 Nov 25 1
6 10660618 MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J Biol Chem 2000 Feb 11 3
7 10722711 Cbfa1 is a positive regulatory factor in chondrocyte maturation. J Biol Chem 2000 Mar 24 1
8 11106645 Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes. J Biol Chem 2001 Mar 9 1
9 11451945 Role of Cbfa1 in ameloblastin gene transcription. J Biol Chem 2001 Sep 14 1
10 11500942 Characterization of the upstream mouse Cbfa1/Runx2 promoter. J Cell Biochem 2001 2
11 11606432 1-(5-oxohexyl)-3,7-Dimethylxanthine, a phosphodiesterase inhibitor, activates MAPK cascades and promotes osteoblast differentiation by a mechanism independent of PKA activation (pentoxifylline promotes osteoblast differentiation). Endocrinology 2001 Nov 4
12 11771853 Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner. Methods Find Exp Clin Pharmacol 2001 Sep 8
13 11787057 Estrogen-induced osteogenesis in mice is associated with the appearance of Cbfa1-expressing bone marrow cells. J Cell Biochem 2002 1
14 11792318 The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 2002 Jan 11 2
15 11856644 The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro. Bone 2002 Feb 2
16 11917107 Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation. Proc Natl Acad Sci U S A 2002 Apr 2 3
17 12110689 Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2. J Biol Chem 2002 Sep 27 1
18 12412799 Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. J Bone Miner Res 2002 Nov 1
19 12606540 Distinct transglutaminase 2-independent and transglutaminase 2-dependent pathways mediate articular chondrocyte hypertrophy. J Biol Chem 2003 May 23 1
20 12649288 Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage. J Biol Chem 2003 Jun 6 3
21 12674336 Fibroblast growth factors lead to increased Msx2 expression and fusion in calvarial sutures. J Bone Miner Res 2003 Apr 1
22 12773122 Hedgehog signaling enhances core-binding factor a1 and receptor activator of nuclear factor-kappaB ligand (RANKL) gene expression in chondrocytes. J Endocrinol 2003 Jun 2
23 12798155 Cbfa1/Runx2 gene expression in articular chondrocytes of the mice temporomandibular and knee joints in vivo. Arch Oral Biol 2003 Jul 1
24 12963046 BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2. Biochem Biophys Res Commun 2003 Sep 26 4
25 14702386 Runx2 deficiency in chondrocytes causes adipogenic changes in vitro. J Cell Sci 2004 Jan 26 1
26 15226309 Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling. J Cell Biol 2004 Jul 5 4
27 15368363 Dexamethasone inhibits insulin-induced chondrogenesis of ATDC5 cells by preventing PI3K-Akt signaling and DNA binding of Runx2. J Cell Biochem 2004 Oct 1 5
28 15517598 Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro. J Cell Biochem 2005 Jan 1 1
29 15591153 Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 2005 Mar 1
30 15842922 [Osteogenesis of rabbit skin fibroblast transfected with core binding factor a1/osteoblast specific transplanting factor-2 gene]. Zhonghua Wai Ke Za Zhi 2005 Feb 15 3
31 16170444 Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line. Osteoporos Int 2005 Dec 2
32 16195230 The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin. J Biol Chem 2005 Dec 9 1
33 16350840 Effects of retinoic acid on the differentiation of chondrogenic progenitor cells, ATDC5. J Med Dent Sci 2005 Sep 2
34 16360153 Dimethyl sulfoxide as an inducer of differentiation in preosteoblast MC3T3-E1 cells. FEBS Lett 2006 Jan 9 1
35 16377268 Type II/III Runx2/Cbfa1 is required for tooth germ development. Bone 2006 Jun 2
36 16419041 Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2. J Cell Physiol 2006 May 1
37 16421932 Runx2 phosphorylation induced by fibroblast growth factor-2/protein kinase C pathways. Proteomics 2006 Feb 2
38 16476422 PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Dev Biol 2006 Apr 1 4
39 16476583 Role of Cbfa1/Runx2 in the fluid shear stress induction of COX-2 in osteoblasts. Biochem Biophys Res Commun 2006 Mar 24 2
40 16496016 Inducible regulation of Runx2-stimulated osteogenesis. Gene Ther 2006 Jun 4
41 16598781 Modulation of mouse RANKL gene expression by Runx2 and PKA pathway. J Cell Biochem 2006 Aug 15 2
42 16636074 Cbfa-1 mediates nitric oxide regulation of MMP-13 in osteoblasts. J Cell Sci 2006 May 1 2
43 16670084 Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells. J Biol Chem 2006 Jul 14 1
44 16868966 Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis Rheum 2006 Aug 1
45 16914731 Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer. Mol Cell Biol 2006 Sep 1
46 16927309 Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation. J Cell Biochem 2007 Feb 1 1
47 16949358 Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation. Bone 2007 Jan 4
48 17031848 Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway. J Cell Biochem 2007 Apr 1 4
49 17051597 Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2. J Cell Physiol 2007 Jan 1
50 17117476 Osteoblast response to titanium regulates transcriptional activity of Runx2 through MAPK pathway. J Biomed Mater Res A 2007 May 2