| Protein Name | kynurenine aminotransferase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 883 |
| Gene Symbol | KYAT1 |
| UniProt | Q16773 (KAT1_HUMAN), B7Z4W5 (B7Z4W5_HUMAN), A8K563 (A8K563_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
116
Total Number of Articles : 71 |
Description |
kynurenine aminotransferase 1 |
| Gene Summary |
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
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