kynurenine aminotransferase 1 ; Homo sapiens






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1 2029638 Two kynurenine aminotransferases in human brain. Brain Res 1991 Mar 1 4
2 2139845 Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity. Drug Metab Dispos 1990 Jan-Feb 1
3 7142182 The heparin-enhanced antithrombin III/thrombin reaction is saturable with respect to both thrombin and antithrombin III. J Biol Chem 1982 Dec 10 1
4 7883047 Molecular cloning and expression of a cDNA for human kidney cysteine conjugate beta-lyase. FEBS Lett 1995 Mar 6 4
5 8294935 Purification and characterization of kynurenine aminotransferase I from human brain. J Neurochem 1994 Feb 10
6 8350986 Characterization of human brain kynurenine aminotransferases using [3H]kynurenine as a substrate. Neuroscience 1993 Jul 7
7 8601430 Functional expression of the plant K+ channel KAT1 in insect cells. FEBS Lett 1996 Feb 19 2
8 8637415 Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome. Life Sci 1996 1
9 8975632 Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation. Arch Toxicol 1996 4
10 9368418 Expression of a Cs(+)-resistant guard cell K+ channel confers Cs(+)-resistant, light-induced stomatal opening in transgenic arabidopsis. Plant Cell 1997 Oct 1
11 9813614 A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis. Scanning Microsc 1996 2
12 10077678 Channel-mediated high-affinity K+ uptake into guard cells from Arabidopsis. Proc Natl Acad Sci U S A 1999 Mar 16 1
13 10206968 Distinct molecular bases for pH sensitivity of the guard cell K+ channels KST1 and KAT1. J Biol Chem 1999 Apr 23 4
14 10945349 Co-expression of calcium-dependent protein kinase with the inward rectified guard cell K+ channel KAT1 alters current parameters in Xenopus laevis oocytes. Plant Cell Physiol 2000 Jun 1
15 10982437 Distinct abscisic acid signaling pathways for modulation of guard cell versus mesophyll cell potassium channels revealed by expression studies in Xenopus laevis oocytes. Plant Physiol 2000 Sep 1
16 11073935 A Xanthomonas alkyl hydroperoxide reductase subunit C (ahpC) mutant showed an altered peroxide stress response and complex regulation of the compensatory response of peroxide detoxification enzymes. J Bacteriol 2000 Dec 1
17 11080307 Inward potassium channel in guard cells as a target for polyamine regulation of stomatal movements. Plant Physiol 2000 Nov 3
18 11170833 Kynurenine aminotransferase I activity in human placenta. Placenta 2001 Feb-Mar 5
19 11402172 Internal aluminum block of plant inward K(+) channels. Plant Cell 2001 Jun 2
20 11736651 Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. Biochem J 2001 Dec 15 1
21 11985333 N(G)-nitro-L-arginine and its methyl ester inhibit brain synthesis of kynurenic acid possibly via nitric oxide-independent mechanism. Pol J Pharmacol 2001 Nov-Dec 4
22 15016471 The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochem Int 2004 Jun 22
23 15364907 Crystal structure of human kynurenine aminotransferase I. J Biol Chem 2004 Nov 26 8
24 15606768 pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I. Eur J Biochem 2004 Dec 8
25 15996837 A case study of acute human chlorpyrifos poisoning: novel aspects on metabolism and toxicokinetics derived from liquid chromatography-tandem mass spectrometry analysis of urine samples. Toxicol Lett 2005 Dec 15 2
26 16088227 Age-related increase of kynurenic acid in human cerebrospinal fluid - IgG and beta2-microglobulin changes. Neurosignals 2005 1
27 16263909 KAT1 inactivates at sub-millimolar concentrations of external potassium. J Exp Bot 2005 Dec 1
28 16950859 Diacidic motif is required for efficient transport of the K+ channel KAT1 to the plasma membrane. Plant Physiol 2006 Nov 3
29 17023091 Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease. Neurochem Int 2007 Jan 3
30 17112493 Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. Clin Chim Acta 2007 Feb 6
31 17360902 HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2. J Neurosci 2007 Mar 14 2
32 17442055 Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain. J Neurochem 2007 Jul 2
33 17504201 Peripheral kynurenine metabolism in focal dystonia. Med Chem 2007 May 4
34 17594596 Immunohistochemical identification of kynurenine aminotransferases in corpora amylacea in the human retina and optic nerve. Folia Neuropathol 2007 1
35 17696489 Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds. Chem Res Toxicol 2008 Jan 2
36 18056996 Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia. J Biol Chem 2008 Feb 8 1
37 18186649 Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry 2008 Feb 12 2
38 19029248 Biochemical and structural properties of mouse kynurenine aminotransferase III. Mol Cell Biol 2009 Feb 1
39 19181866 The guard cell as a single-cell model towards understanding drought tolerance and abscisic acid action. J Exp Bot 2009 1
40 19326339 Bioactivation of selenocysteine derivatives by beta-lyases present in common gastrointestinal bacterial species. Int J Vitam Nutr Res 2008 Jul-Sep 2
41 19338303 Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K. J Med Chem 2009 May 14 9
42 19584079 Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells. Cancer Prev Res (Phila) 2009 Jul 15
43 19826765 Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Cell Mol Life Sci 2010 Feb 1
44 20663906 Occupational trichloroethylene exposure and renal carcinoma risk: evidence of genetic susceptibility by reductive metabolism gene variants. Cancer Res 2010 Aug 15 2
45 20712625 Trafficking, lateral mobility and segregation of the plant K channel KAT1. Plant Biol (Stuttg) 2010 Sep 1
46 20949433 Measurement of cysteine S-conjugate β-lyase activity. Curr Protoc Toxicol 2010 May 1
47 21660485 New insight into the antidepressants action: modulation of kynurenine pathway by increasing the kynurenic acid/3-hydroxykynurenine ratio. J Neural Transm (Vienna) 2012 Feb 4
48 21925563 Food and Chemical Toxicology, 2011, 'Possible role of cysteine-S-conjugate β-lyase in species differences in cisplatin nephrotoxicity', R. Katayama, S. Nagata, H. Iida, N. Yamagishi, T. Yamashita, K. Furuhama. Food Chem Toxicol 2011 Dec 1
49 22093698 New insights into the metabolism of organomercury compounds: mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine γ-lyase. Arch Biochem Biophys 2012 Jan 1 7
50 22281190 Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I. Bioorg Med Chem Lett 2012 Feb 15 5