methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit ; Homo sapiens






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1 3029112 Inhibition of methylation at two internal N6-methyladenosine sites caused by GAC to GAU mutations. J Biol Chem 1987 Mar 5 1
2 9409616 Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase. RNA 1997 Nov 2
3 11470232 Expression of the mRNA (N6-adenosine)-methyltransferase S-adenosyl-L-methionine binding subunit mRNA in cultured cells. Int J Biochem Cell Biol 2001 Oct 1
4 11551827 Methionine depletion induces transcription of the mRNA (N6-adenosine)methyltransferase. Int J Biochem Cell Biol 2001 Nov 4
5 12355263 Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase. J Mol Evol 2002 Oct 2
6 16684535 Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase. FEBS Lett 2006 May 29 2
7 24316715 A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol 2014 Feb 1
8 24407421 Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Res 2014 Feb 5
9 24481042 Methyltransferases modulate RNA stability in embryonic stem cells. Nat Cell Biol 2014 Feb 1
10 24939862 [2+2+1] cycloadditions of bis(dialkylamino)acetylenes with SiI2(Idip): syntheses and reactivity studies of unprecedented 2,3,4,5-tetraamino-1 H-siloles. Chemistry 2014 Jul 21 25
11 24981863 Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep 2014 Jul 10 1
12 26323656 Structural and Functional Characterization of the Proteins Responsible for N(6)-Methyladenosine Modification and Recognition. Curr Protein Pept Sci 2016 2
13 26526723 Coordination of m(6)A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming. Cell Stem Cell 2015 Dec 3 1
14 26643712 Iron- and Cobalt-Catalyzed Synthesis of Carbene Phosphinidenes. Angew Chem Int Ed Engl 2016 Jan 26 12
15 27103452 RNA epigenetic modification: N6-methyladenosine. Yi Chuan 2016 Apr 4
16 27117702 The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell 2016 May 5 1
17 27153530 METTL3 Gains R/W Access to the Epitranscriptome. Mol Cell 2016 May 5 1
18 27281194 Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex. Nature 2016 Jun 23 5
19 27373337 Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Mol Cell 2016 Jul 21 3
20 27773535 N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe 2016 Nov 9 1
21 27919081 m<sup>6</sup>A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination. Nature 2016 Dec 8 1
22 28027310 m6A-Driver: Identifying Context-Specific mRNA m6A Methylation-Driven Gene Interaction Networks. PLoS Comput Biol 2016 Dec 1
23 28067455 Room Temperature Regioselective Catalytic Hydrodefluorination of Fluoroarenes with trans-[Ru(NHC)<sub>4</sub> H<sub>2</sub> ] through a Concerted Nucleophilic Ru-H Attack Pathway. Angew Chem Int Ed Engl 2017 Feb 1 1
24 28099411 Corrigendum: Structural basis of N<sup>6</sup>-adenosine methylation by the METTL3-METTL14 complex. Nature 2017 Feb 9 1
25 28247949 NSUN2-Mediated m5C Methylation and METTL3/METTL14-Mediated m6A Methylation Cooperatively Enhance p21 Translation. J Cell Biochem 2017 Sep 1
26 28297667 m<sup>6</sup>A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep 2017 Mar 14 1
27 28611253 <i>N</i><sup>6</sup>-methyladenosine is required for the hypoxic stabilization of specific mRNAs. RNA 2017 Sep 1
28 28624569 Readers, writers and erasers of N<sup>6</sup>-methylated adenosine modification. Curr Opin Struct Biol 2017 Dec 1
29 28854373 Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs. Cell Rep 2017 Aug 29 1
30 28867248 Roles of RNA methylation by means of N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) in human cancers. Cancer Lett 2017 Nov 1 1
31 28878038 The requirement of Mettl3-promoted <i>MyoD</i> mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation. Open Biol 2017 Sep 4
32 29051200 Human METTL16 is a <i>N</i><sup>6</sup>-methyladenosine (m<sup>6</sup>A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. EMBO Rep 2017 Nov 1
33 29116772 N<sup>6</sup>-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay. J Am Chem Soc 2017 Dec 6 1
34 29171881 RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2. Hepatology 2018 Jun 1
35 29174803 HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g. Cancer Lett 2018 Feb 28 4
36 29335608 N<sup>6</sup>-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications. Nat Neurosci 2018 Feb 4
37 29345285 The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells. Int J Oncol 2018 Feb 4
38 29348140 Interactions, localization, and phosphorylation of the m<sup>6</sup>A generating METTL3-METTL14-WTAP complex. RNA 2018 Apr 1
39 29489750 The SMAD2/3 interactome reveals that TGFβ controls m<sup>6</sup>A mRNA methylation in pluripotency. Nature 2018 Mar 8 3
40 29502358 METTL3 regulates alternative splicing of MyD88 upon the lipopolysaccharide-induced inflammatory response in human dental pulp cells. J Cell Mol Med 2018 May 2
41 29506078 SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function. Nucleic Acids Res 2018 Jun 1 4
42 29542011 Solution structure of the RNA recognition domain of METTL3-METTL14 N<sup>6</sup>-methyladenosine methyltransferase. Protein Cell 2019 Apr 2
43 29659627 N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection. PLoS Pathog 2018 Apr 1
44 29680375 N<sup>6</sup>-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells. Toxicol Lett 2018 Aug 8
45 29795472 Maternal obesity aggravates the abnormality of porcine placenta by increasing N<sup>6</sup>-methyladenosine. Int J Obes (Lond) 2018 Oct 1
46 29909453 m<sup>6</sup>A RNA Methylation Controls Neural Development and Is Involved in Human Diseases. Mol Neurobiol 2019 Mar 1
47 29913347 Structural basis for eukaryotic mRNA modification. Curr Opin Struct Biol 2018 Dec 2
48 29978784 [Methyltransferase-like 3 Promotes the Proliferation of Acute Myeloid Leukemia Cells by Regulating N6-methyladenosine Levels of MYC]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Jun 28 2
49 30038300 METTL3 regulates WTAP protein homeostasis. Cell Death Dis 2018 Jul 23 2
50 30048615 The Role of m<sup>6</sup>A/m-RNA Methylation in Stress Response Regulation. Neuron 2018 Jul 25 1