Pub. Date : 2018 Feb
PMID : 29345285
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | N6-methyladenosine (m6A) is the most abundant epitranscriptome modification in mammalian mRNA. | N-methyladenosine | methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit | Homo sapiens |
2 | Although morphologic and proliferative changes were unaffected, METTL3-depleted cells showed higher sensitivity to anticancer reagents such as gemcitabine, 5-fluorouracil, cisplatin and irradiation. | gemcitabine | methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit | Homo sapiens |
3 | Although morphologic and proliferative changes were unaffected, METTL3-depleted cells showed higher sensitivity to anticancer reagents such as gemcitabine, 5-fluorouracil, cisplatin and irradiation. | Fluorouracil | methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit | Homo sapiens |
4 | Although morphologic and proliferative changes were unaffected, METTL3-depleted cells showed higher sensitivity to anticancer reagents such as gemcitabine, 5-fluorouracil, cisplatin and irradiation. | Cisplatin | methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit | Homo sapiens |