| 1 | 1376108 | Structural and computational investigations of the conformation of antigenic peptide fragments of human polymorphic epithelial mucin. | Biochem J | 1992 May 15 |
2 |
| 2 | 6430360 | Amine inversion in proteins. A 13C-NMR study of proton exchange and nitrogen inversion rates in N epsilon,N epsilon,N alpha,N alpha-[13C]tetramethyllysine,N epsilon,N epsilon,N alpha,N alpha-[13C]tetramethyllysine methyl ester, and reductively methylated concanavalin A. | Biophys Chem | 1984 Jun |
1 |
| 3 | 7858534 | Carmustine, Ara C, cyclophosphamide and etoposide with autologous bone marrow transplantation in relapsed or refractory lymphoma: a dose-finding study. | Bone Marrow Transplant | 1994 Oct |
3 |
| 4 | 8702610 | A role in enzyme activation for the N-terminal leader sequence in calmodulin. | J Biol Chem | 1996 Aug 9 |
1 |
| 5 | 9521123 | A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometry. | Protein Sci | 1998 Feb |
1 |
| 6 | 10231551 | Characterization of the myosin light chain kinase from smooth muscle as an actin-binding protein that assembles actin filaments in vitro. | Biochim Biophys Acta | 1999 May 6 |
1 |
| 7 | 10525402 | Crystal structure of the C-terminal SH2 domain of the p85alpha regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate. | J Mol Biol | 1999 Oct 1 |
3 |
| 8 | 10574939 | Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein. | J Biol Chem | 1999 Dec 3 |
3 |
| 9 | 10587314 | Structure investigation of amphiphilic cyclopeptides in isotropic and anisotropic environments-A model study simulating peptide-membrane interactions. | J Pept Sci | 1999 Nov |
2 |
| 10 | 10656250 | Identification of a novel aspartic protease (Asp 2) as beta-secretase. | Mol Cell Neurosci | 1999 Dec |
1 |
| 11 | 10677483 | Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein. | Proc Natl Acad Sci U S A | 2000 Feb 15 |
3 |
| 12 | 10684253 | Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidation. | J Cell Biol | 2000 Feb 21 |
1 |
| 13 | 10801872 | Maturation and pro-peptide cleavage of beta-secretase. | J Biol Chem | 2000 Oct 6 |
1 |
| 14 | 10887202 | Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties. | J Biol Chem | 2000 Jul 14 |
2 |
| 15 | 10924510 | Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase. | J Biol Chem | 2000 Oct 27 |
11 |
| 16 | 10956649 | A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase. | J Biol Chem | 2000 Dec 1 |
9 |
| 17 | 11015226 | Proteolytic activation of recombinant pro-memapsin 2 (pro-beta-secretase) studied with new fluorogenic substrates. | Biochemistry | 2000 Oct 10 |
4 |
| 18 | 11071887 | Processing of beta-secretase by furin and other members of the proprotein convertase family. | J Biol Chem | 2001 Feb 9 |
1 |
| 19 | 11152688 | Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production. | J Biol Chem | 2001 Apr 6 |
2 |
| 20 | 11179458 | Characterization of recombinant, soluble beta-secretase from an insect cell expression system. | Mol Pharmacol | 2001 Mar |
1 |
| 21 | 11211053 | Amyloid precursor protein beta-secretase (BACE) mRNA expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines and growth factors. | Neuropathology | 2000 Dec |
1 |
| 22 | 11266439 | The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain. | J Biol Chem | 2001 Mar 30 |
3 |
| 23 | 11278492 | Characterization of the glycosylation profiles of Alzheimer's beta -secretase protein Asp-2 expressed in a variety of cell lines. | J Biol Chem | 2001 May 18 |
2 |
| 24 | 11278841 | Phosphorylation regulates intracellular trafficking of beta-secretase. | J Biol Chem | 2001 May 4 |
1 |
| 25 | 11306583 | Mechanism of Inhibition of beta-site amyloid precursor protein-cleaving enzyme (BACE) by a statine-based peptide. | J Biol Chem | 2001 Jun 29 |
3 |
| 26 | 11513577 | Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design. | Biochemistry | 2001 Aug 28 |
3 |
| 27 | 11525745 | Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts. | Curr Biol | 2001 Aug 21 |
2 |
| 28 | 11716984 | The functional gamma-secretase inhibitor prevents production of amyloid beta 1-34 in human and murine cell lines. | Neurosci Lett | 2001 Nov 27 |
2 |
| 29 | 11741910 | Substrate and inhibitor profile of BACE (beta-secretase) and comparison with other mammalian aspartic proteases. | J Biol Chem | 2002 Feb 15 |
1 |
| 30 | 11763362 | Conformation of N-terminal HIV-1 Tat (fragment 1-9) peptide by NMR and MD simulations. | J Pept Sci | 2001 Nov |
1 |
| 31 | 11784130 | Design of substrate-based inhibitors of human beta-secretase. | J Med Chem | 2002 Jan 17 |
2 |
| 32 | 11847218 | Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain. | J Biol Chem | 2002 May 3 |
1 |
| 33 | 11860271 | The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta). | Mol Cell Neurosci | 2002 Feb |
3 |
| 34 | 11922623 | Prediction of the tertiary structure of the beta-secretase zymogen. | Biochem Biophys Res Commun | 2002 Apr 5 |
2 |
| 35 | 11953458 | The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity. | J Neurochem | 2002 Mar |
5 |
| 36 | 12064471 | Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles. | J Neurochem | 2002 Apr |
1 |
| 37 | 12206667 | Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3. | Biochemistry | 2002 Sep 10 |
6 |
| 38 | 12270690 | Oxidative stress increases expression and activity of BACE in NT2 neurons. | Neurobiol Dis | 2002 Aug |
8 |
| 39 | 12356481 | Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography. | Protein Expr Purif | 2002 Oct |
1 |
| 40 | 12458195 | Kinetic studies on beta-site amyloid precursor protein-cleaving enzyme (BACE). Confirmation of an iso mechanism. | J Biol Chem | 2003 Feb 14 |
5 |
| 41 | 12473667 | Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1). | J Biol Chem | 2003 Apr 25 |
4 |
| 42 | 12551920 | Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation. | J Biol Chem | 2003 May 9 |
3 |
| 43 | 12586838 | Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)). | J Biol Chem | 2003 Apr 25 |
3 |
| 44 | 12649271 | Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis. | J Biol Chem | 2003 May 30 |
3 |
| 45 | 12723942 | Design and synthesis of statine-based cell-permeable peptidomimetic inhibitors of human beta-secretase. | J Med Chem | 2003 May 8 |
4 |
| 46 | 12736275 | BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors. | J Biol Chem | 2003 Jul 11 |
2 |
| 47 | 14501002 | Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP). | J Mol Neurosci | 2003 |
2 |
| 48 | 14504402 | Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein. | Proc Natl Acad Sci U S A | 2003 Sep 30 |
3 |
| 49 | 14530380 | Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase. | J Cell Biol | 2003 Oct 13 |
7 |
| 50 | 14567678 | Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. | Biochemistry | 2003 Oct 28 |
4 |