acyl-CoA dehydrogenase medium chain ; Rattus norvegicus






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1 1931995 Spiropentaneacetic acid as a specific inhibitor of medium-chain acyl-CoA dehydrogenase. Biochemistry 1991 Nov 5 2
2 3611054 Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat liver medium chain acyl coenzyme A dehydrogenase. J Biol Chem 1987 Jul 25 2
3 7703241 Medium-chain acyl-CoA dehydrogenase- and enoyl-CoA hydratase-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoyl-CoA. Biochemistry 1995 Apr 4 6
4 7829528 Isoalloxazine ring of FAD is required for the formation of the core in the Hsp60-assisted folding of medium chain acyl-CoA dehydrogenase subunit into the assembly competent conformation in mitochondria. J Biol Chem 1995 Jan 27 9
5 7971999 The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A 1994 Nov 8 3
6 8109745 Specific assay of medium-chain acyl-CoA dehydrogenase based on the spectrophotometric measurement of product formation. Anal Biochem 1993 Nov 1 2
7 8314750 Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element. J Biol Chem 1993 Jul 5 4
8 8615829 Transcriptional regulation by glucocorticoids of mitochondrial oxidative enzyme genes in the developing rat kidney. Biochem J 1996 Apr 15 4
9 8967442 Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle. Am J Physiol 1996 May 2
10 9164869 Tissue-specific regulation of medium-chain acyl-CoA dehydrogenase gene by thyroid hormones in the developing rat. Biochem J 1997 May 15 4
11 9354389 Spectroscopic studies of rat liver acyl-CoA oxidase with reference to recognition and activation of substrate. J Biochem 1997 Jun 4
12 9852194 The energy substrate switch during development of heart failure: gene regulatory mechanisms (Review). Int J Mol Med 1998 Jan 2
13 10200137 Influence of valproic acid on the expression of various acyl-CoA dehydrogenases in rats. Pediatr Int 1999 Feb 1
14 10958805 Mitochondrial transcription factor A is increased but expression of ATP synthase beta subunit and medium-chain acyl-CoA dehydrogenase genes are decreased in hearts of copper-deficient rats. J Nutr 2000 Sep 2
15 11373342 PPARalpha gene expression in the developing rat kidney: role of glucocorticoids. J Am Soc Nephrol 2001 Jun 3
16 11872165 Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase. J Biochem 2002 Mar 8
17 15018640 Relationship between PPARalpha activation and NO on proximal tubular Na+ transport in the rat. BMC Pharmacol 2004 Feb 6 2
18 15358373 Expression and purification of His-tagged rat mitochondrial medium-chain acyl-CoA dehydrogenase wild-type and Arg256 mutant proteins. Protein Expr Purif 2004 Oct 3
19 15852996 Mechanisms of ketamine action on lipid metabolism in rats. Eur J Anaesthesiol 2005 Mar 1
20 15863369 Supplementation with alpha-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of beta-oxidation in Zucker fatty rats. Biochim Biophys Acta 2005 Apr 15 2
21 15927499 Down-regulation of Hsp60 expression by RNAi impairs folding of medium-chain acyl-CoA dehydrogenase wild-type and disease-associated proteins. Mol Genet Metab 2005 Aug 2
22 17352811 Feeding oxidized fat during pregnancy up-regulates expression of PPARalpha-responsive genes in the liver of rat fetuses. Lipids Health Dis 2007 Mar 12 1
23 18171348 PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes. J Gastroenterol Hepatol 2008 Jan 1
24 18456726 The benefit of medium-chain triglyceride therapy on the cardiac function of SHRs is associated with a reversal of metabolic and signaling alterations. Am J Physiol Heart Circ Physiol 2008 Jul 2
25 19699196 Adenosine monophosphate-activated protein kinase inhibits cardiac hypertrophy through reactivating peroxisome proliferator-activated receptor-alpha signaling pathway. Eur J Pharmacol 2009 Oct 12 3
26 20011657 Fasting Upregulates PPARalpha Target Genes in Brain and Influences Pituitary Hormone Expression in a PPARalpha Dependent Manner. PPAR Res 2009 1
27 21169901 Carnitine regulates myocardial metabolism by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) in alcoholic cardiomyopathy. Med Sci Monit 2011 Jan 2
28 21310443 Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo. Metabolism 2011 Aug 1
29 21700370 Oleate-enriched diet improves insulin sensitivity and restores muscle protein synthesis in old rats. Clin Nutr 2011 Dec 1
30 22738961 Angelica keiskei extract improves insulin resistance and hypertriglyceridemia in rats fed a high-fructose drink. Biosci Biotechnol Biochem 2012 2
31 22874759 Disorder of fatty acid metabolism in the kidney of PAN-induced nephrotic rats. Am J Physiol Renal Physiol 2012 Oct 2
32 25132363 The flavan-3-ol fraction of cocoa powder suppressed changes associated with early-stage metabolic syndrome in high-fat diet-fed rats. Life Sci 2014 Sep 26 2
33 26068433 Herbal composition Gambigyeongsinhwan (4) from Curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka Long-Evans Tokushima Fatty rats. J Ethnopharmacol 2015 Aug 2 1
34 26949064 Effect of clofibrate on fatty acid metabolism in the kidney of puromycin-induced nephrotic rats. Clin Exp Nephrol 2016 Dec 1
35 29278547 Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection. J Hypertens 2018 May 1
36 30138942 Targeting Peroxisome Proliferator Activated Receptor α (PPAR α) for the Prevention of Mitochondrial Impairment and Hypertrophy in Cardiomyocytes. Cell Physiol Biochem 2018 1
37 30935417 The sodium-glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats. Cardiovasc Diabetol 2019 Apr 1 1
38 33755174 Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells. J Mol Cell Biol 2021 Sep 11 3
39 34732632 A New Perspective on Fish Oil: The Prevention of Alcoholic Liver Disease. J Oleo Sci 2021 2
40 34923497 Endurance Exercise Training-Attenuated Diabetic Kidney Disease with Muscle Weakness in Spontaneously Diabetic Torii Fatty Rats. Kidney Blood Press Res 2022 1
41 34939931 Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation. Elife 2021 Dec 23 6