fragile histidine triad diadenosine triphosphatase ; Homo sapiens






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1 3125959 Translocation t(3;8)(p14.2;q24.1) in renal cell carcinoma affects expression of the common fragile site at 3p14(FRA3B) in lymphocytes. Cancer Genet Cytogenet 1988 Mar 1
2 3137811 Chromosome breakage and recombination at fragile sites. Am J Hum Genet 1988 Sep 1
3 3681903 The effect of hydroxyurea on the expression of the common fragile site at 3p14. J Med Genet 1987 Oct 6
4 3793108 The effect of 1-beta-D-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14. Hum Genet 1986 Dec 5
5 7492590 Specific dinucleoside polyphosphate cleaving enzymes from chromaffin cells: a fluorimetric study. Biochim Biophys Acta 1995 Nov 15 1
6 7533524 Integrated YAC contig containing the 3p14.2 hereditary renal carcinoma 3;8 translocation breakpoint and the fragile site FRA3B. Genes Chromosomes Cancer 1994 Dec 1
7 7558007 Precise localization of aphidicolin-induced breakpoints on the short arm of human chromosome 3. Genomics 1995 May 20 1
8 7806217 Multicolor FISH mapping of YAC clones in 3p14 and identification of a YAC spanning both FRA3B and the t(3;8) associated with hereditary renal cell carcinoma. Genomics 1994 Jul 15 3
9 8661108 A 350-kb cosmid contig in 3p14.2 that crosses the t(3;8) hereditary renal cell carcinoma translocation breakpoint and 17 aphidicolin-induced FRA3B breakpoints. Genomics 1996 Jul 1 1
10 8764101 The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res 1996 Jul 15 1
11 8794732 Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. Biochemistry 1996 Sep 10 3
12 8824874 FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Hum Mol Genet 1996 Feb 2
13 9157994 Abnormal FHIT transcripts in human breast carcinomas: a clinicopathological and epidemiological analysis of 61 Japanese cases. Cancer Res 1997 May 15 1
14 9169152 Aphidicolin-induced FRA3B breakpoints cluster in two distinct regions. Genomics 1997 May 1 2
15 9170214 Decreased or altered expression of the FHIT gene in human leukemias. Stem Cells 1997 1
16 9178887 Frequent breakpoints in the region surrounding FRA3B in sporadic renal cell carcinomas. Oncogene 1997 Mar 20 1
17 9261067 MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family. Structure 1997 Jun 15 5
18 9290961 Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines. Genes Chromosomes Cancer 1997 Sep 2
19 9401074 Aberrant FHIT transcripts in acute myeloid leukaemia. Br J Haematol 1997 Dec 1
20 9499431 Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. Hum Mol Genet 1998 Apr 3
21 9521166 Protein expression and functional analysis of the FHIT gene in human tumor cells. J Natl Cancer Inst 1998 Mar 18 1
22 9537583 Analysis of FHIT transcripts in cervical and endometrial cancers. Int J Cancer 1998 Apr 13 1
23 9543008 Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein. Protein Eng 1997 Dec 2
24 9559339 An FHIT tumor suppressor gene? Genes Chromosomes Cancer 1998 Apr 1
25 9573184 Control of 5',5'-dinucleoside triphosphate catabolism by APH1, a Saccharomyces cerevisiae analog of human FHIT. J Bacteriol 1998 May 2
26 9576908 Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc Natl Acad Sci U S A 1998 May 12 9
27 9621287 The genetics of renal tumors in end-stage renal failure differs from those occurring in the general population. J Am Soc Nephrol 1998 Jun 1
28 9671749 Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. Proc Natl Acad Sci U S A 1998 Jul 21 2
29 9699676 Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res 1998 Aug 1 2
30 9713284 Expression of abnormal transcripts of the FHIT (fragile histidine triad) gene in ovarian carcinoma. Eur J Cancer 1998 Apr 2
31 9744812 T4 DNA ligase synthesizes dinucleoside polyphosphates. FEBS Lett 1998 Aug 21 6
32 9824201 Study of FHIT transcripts in normal and malignant breast tissue. Genes Chromosomes Cancer 1998 Dec 1
33 9885976 Abnormal FHIT transcripts found in both lung cancer and normal lung tissue. Genes Chromosomes Cancer 1999 Feb 1
34 9926922 Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia. Oncogene 1999 Jan 7 1
35 9949202 Allele-specific late replication and fragility of the most active common fragile site, FRA3B. Hum Mol Genet 1999 Mar 1
36 10027001 The role of deletions at the FRA3B/FHIT locus in carcinogenesis. Recent Results Cancer Res 1998 4
37 10027335 A possible involvement of aberrant expression of the FHIT gene in the carcinogenesis of squamous cell carcinoma of the uterine cervix. Br J Cancer 1999 Feb 1
38 10063967 FHITness and cancer. Oncol Res 1998 1
39 10090754 Stereochemical retention of the configuration in the action of Fhit on phosphorus-chiral substrates. Biochemistry 1999 Mar 23 18
40 10223242 Fragile histidine triad transcription abnormalities and human papillomavirus E6-E7 mRNA expression in the development of cervical carcinoma. Cancer 1999 May 1 1
41 10377436 Cancer-specific chromosome alterations in the constitutive fragile region FRA3B. Proc Natl Acad Sci U S A 1999 Jun 22 2
42 10407161 Fluorimetric detection of enzymatic activity associated with the human tumor suppressor Fhit protein. Biochim Biophys Acta 1999 Jul 13 6
43 10411902 The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control. Proc Natl Acad Sci U S A 1999 Jul 20 1
44 10416589 Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. Cancer Res 1999 Jul 15 2
45 10440747 FHIT gene in gastric cancer: association with tumour progression and prognosis. J Pathol 1999 Aug 2
46 10497298 The histidine triad superfamily of nucleotide-binding proteins. J Cell Physiol 1999 Nov 2
47 10530564 Different immunohistochemical patterns of Fhit protein expression in renal neoplasms. Mod Pathol 1999 Oct 1
48 10551739 Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas. J Oral Pathol Med 1999 Nov 3
49 10585575 FHIT alterations in cancerous and non-cancerous cervical epithelium. Int J Cancer 2000 Jan 1 1
50 10589760 Aberrant fragile histidine triad gene transcripts in primary hepatocellular carcinoma and liver cirrhosis. Clin Cancer Res 1999 Nov 1