secreted phosphoprotein 1 ; Mus musculus






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1 1497879 Regulated temporal and spatial expression of the calcium-binding proteins calcyclin and OPN (osteopontin) in mouse tissues during pregnancy. Mol Reprod Dev 1992 Aug 1
2 1567180 Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. Anticancer Res 1992 Jan-Feb 6
3 1633816 Characterization of the promoter region of the porcine opn (osteopontin, secreted phosphoprotein 1) gene. Identification of positive and negative regulatory elements and a 'silent' second promoter. Eur J Biochem 1992 Jul 15 3
4 1665202 DNA binding properties of the vitamin D3 receptor zinc finger region. Mol Endocrinol 1991 Dec 2
5 2009532 1 alpha,25-dihydroxyvitamin D3 stimulates synthesis and secretion of nonphosphorylated osteopontin (secreted phosphoprotein 1) in mouse JB6 epidermal cells. Cancer Res 1991 Apr 15 2
6 2055467 The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone. Gene 1991 Apr 2
7 2095355 Interleukin 1 regulates the expression of osteopontin mRNA by osteoblasts. Mol Cell Endocrinol 1990 Dec 21 2
8 2175918 Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. Proc Natl Acad Sci U S A 1990 Dec 6
9 2722855 Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J Biol Chem 1989 Jun 5 1
10 3339096 Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol 1988 Feb 1
11 7506262 Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. J Biol Chem 1994 Jan 7 2
12 7525433 [Studies on expression and function of Eta-1(early T lymphocyte activation-1) in autoimmune prone MRL/Mp-lpr/lpr mice]. Hokkaido Igaku Zasshi 1994 Jul 1
13 7542253 Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions. J Cell Biochem 1995 Apr 10
14 7544276 Establishment and characterization of bone marrow stromal cell lines that support osteoclastogenesis. Endocrinology 1995 Sep 2
15 7687432 Mouse osteopontin expressed in E. coli exhibits autophosphorylating activity of tyrosine residues. Biochem Biophys Res Commun 1993 Jul 15 4
16 7746099 Retinoic acid induces osteoclast-like cell formation by directly acting on hemopoietic blast cells and stimulates osteopontin mRNA expression in isolated osteoclasts. Life Sci 1995 1
17 7784060 Expression of antisense osteopontin RNA inhibits tumor promoter-induced neoplastic transformation of mouse JB6 epidermal cells. Oncogene 1995 Jun 1 3
18 7785891 Conformational analyses on soluble and surface bound osteopontin. Ann N Y Acad Sci 1995 Apr 21 1
19 7785897 Effects of okadaic acid on calcitriol- and phorbol ester-induced expression and phosphorylation of osteopontin in mouse JB6 epidermal cells. Ann N Y Acad Sci 1995 Apr 21 2
20 7785911 Expression of osteopontin in a macrophage cell line and in transgenic mice with pulmonary fibrosis resulting from the lung expression of a tumor necrosis factor-alpha transgene. Ann N Y Acad Sci 1995 Apr 21 2
21 8015545 DNA sequences that act as high affinity targets for the vitamin D3 receptor in the absence of the retinoid X receptor. Mol Endocrinol 1994 Mar 2
22 8070379 Calcitriol regulation of osteopontin expression in mouse epidermal cells. Endocrinology 1994 Sep 24
23 8164440 Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. Kidney Int 1994 Feb 1
24 8228520 [The expression of osteoblastic features in a SV40 large T antigen immortalized mouse calvarial cell line]. Kokubyo Gakkai Zasshi 1993 Sep 2
25 8300629 Highly potent transcriptional activation by 16-ene derivatives of 1,25-dihydroxyvitamin D3. Lack of modulation by 9-cis-retinoic acid of response to 1,25-dihydroxyvitamin D3 or its derivatives. J Biol Chem 1994 Jan 28 1
26 8425206 Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin. Cancer Res 1993 Feb 1 2
27 8485706 1 alpha,25-Dihydroxyvitamin D3 enhances 12-O-tetradecanoylphorbol-13-acetate- induced tumorigenic transformation and osteopontin expression in mouse JB6 epidermal cells. Cancer Res 1993 May 15 1
28 8622862 Cells in vivo and in vitro from osteopetrotic mice homozygous for c-src disruption show suppression of synthesis of osteopontin, a multifunctional extracellular matrix protein. Oncogene 1996 Apr 4 2
29 8830797 Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages. J Leukoc Biol 1996 Sep 2
30 8836881 Non-RGD domains of osteopontin promote cell adhesion without involving alpha v integrins. J Cell Biochem 1996 Jul 2
31 8881770 Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice. Immunology 1996 Aug 1
32 8889846 Protein kinases of cultured osteoblasts: selectivity for the extracellular matrix proteins of bone and their catalytic competence for osteopontin. J Bone Miner Res 1996 Oct 1
33 8900396 Analysis of binding of the 1,25-dihydroxyvitamin D3 receptor to positive and negative vitamin D response elements. Arch Biochem Biophys 1996 Oct 15 1
34 9010343 Vitamin D receptor interactions with the murine osteopontin response element. J Steroid Biochem Mol Biol 1996 Dec 1
35 9048346 Secondary hyperparathyroidism and vitamin D receptor binding to vitamin D response elements in rats with incipient renal failure. J Am Soc Nephrol 1997 Feb 1
36 9084659 Protein kinases of cultured chicken osteoblasts that phosphorylate extracellular bone proteins. Connect Tissue Res 1996 1
37 9143355 Salt concentration determines 1,25-dihydroxyvitamin D3 dependency of vitamin D receptor-retinoid X receptor--vitamin D-responsive element complex formation. Arch Biochem Biophys 1997 May 1 1
38 9213220 Expression of the vitamin D and the retinoid X receptors in Saccharomyces cerevisiae: alternative in vivo models for ligand-induced transactivation. J Cell Biochem 1997 Aug 1 1
39 9268918 Vitamin A and carotenoids stimulate differentiation of mouse osteoblastic cells. J Nutr Sci Vitaminol (Tokyo) 1997 Jun 5
40 9342184 Osteopontin expression in mammary gland development and tumorigenesis. Cell Growth Differ 1997 Oct 6
41 9344042 Calcitriol enhancement of TPA-induced tumorigenic transformation is mediated through vitamin D receptor-dependent and -independent pathways. Clin Exp Metastasis 1997 Nov 7
42 9379315 Osteopontin antisense deoxyoligonucleotides inhibit bone resorption by mouse osteoclasts in vitro. J Periodontal Res 1997 Aug 1
43 9525962 Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions. J Biol Chem 1998 Apr 3 1
44 9541257 Characteristics of vitamin D3 receptor (VDR) binding to the vitamin D response element (VDRE) in rat bone sialoprotein gene promoter. Eur J Oral Sci 1998 Jan 2
45 9846278 [Relationship between osteopontin expression and autoimmune disease--analysis of osteopontin expressed in transgenic mice]. Hokkaido Igaku Zasshi 1998 Sep 4
46 9862225 Expression of dentin sialoprotein (DSP) and other molecular determinants by a new cell line from dental papillae, MDPC-23. Connect Tissue Res 1998 1
47 9867126 Enhanced osteopontin expression and macrophage infiltration in MRL-Fas(lpr) mice with lupus nephritis. Autoimmunity 1998 1
48 9933476 Altered expression of bone sialoproteins in vitamin D-deficient rBSP2.7Luc transgenic mice. J Bone Miner Res 1999 Feb 4
49 10234571 Differential effects of 20-epi vitamin D analogs on the vitamin D receptor homodimer. J Bone Miner Res 1999 Apr 1
50 10411681 Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. Kidney Int 1999 Jul 4