SUMO specific peptidase 2 ; Homo sapiens






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1 11489887 Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation. J Biol Chem 2001 Oct 19 1
2 15296745 A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. Structure 2004 Aug 2
3 16738331 Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2. Mol Cell Biol 2006 Jun 3
4 21554500 Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis. Genes Cells 2011 Jun 1
5 23510938 SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons. Channels (Austin) 2013 May-Jun 1
6 23691130 Role of SUMO-specific protease 2 in reprogramming cellular glucose metabolism. PLoS One 2013 9
7 24422630 Transcriptional repression of estrogen receptor α signaling by SENP2 in breast cancer cells. Mol Endocrinol 2014 Feb 1
8 24512059 Identification of 1,2,5-oxadiazoles as a new class of SENP2 inhibitors using structure based virtual screening. J Chem Inf Model 2014 Mar 24 2
9 24586832 Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling. PLoS One 2014 2
10 28470603 A Generic Protocol for Purifying Disulfide-Bonded Domains and Random Protein Fragments Using Fusion Proteins with SUMO3 and Cleavage by SenP2 Protease. Methods Mol Biol 2017 1
11 29050267 Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2. Oncotarget 2017 Sep 19 1
12 29874116 The SUMO-specific isopeptidase SENP2 is targeted to intracellular membranes via a predicted N-terminal amphipathic α-helix. Mol Biol Cell 2018 Aug 1 1
13 29969578 SUMO-specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de-SUMOylation. FASEB J 2019 Jan 2
14 30431078 SENP2 exerts an anti‑tumor effect on chronic lymphocytic leukemia cells through the inhibition of the Notch and NF‑κB signaling pathways. Int J Oncol 2019 Feb 2
15 30940449 SENP2 suppresses NF-κB activation and sensitizes breast cancer cells to doxorubicin. Eur J Pharmacol 2019 Jul 5 9
16 31964975 Silencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation. Sci Rep 2020 Jan 21 7
17 32717481 Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family. Eur J Med Chem 2020 Oct 15 1
18 34331980 Construction and antitumor activity of selenium nanoparticles decorated with the polysaccharide extracted from Citrus limon (L.) Burm. f. (Rutaceae). Int J Biol Macromol 2021 Oct 1 2
19 34909683 SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells. Curr Res Pharmacol Drug Discov 2021 6
20 34950583 SENP2 Reduces Hepatocellular Carcinoma Stemness and Improves Sorafenib Sensitivity Through Inactivating the AKT/GSK3β/CTNNB1 Pathway. Front Oncol 2021 5