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| 3 | 16720724 | FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor. | J Mol Endocrinol | 2006 Jun |
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| 4 | 16917513 | Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis. | Cell Death Differ | 2007 Mar |
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| 5 | 17215250 | Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2. | J Biol Chem | 2007 Apr 6 |
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| 6 | 18208356 | Smurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome pathway. | Biol Chem | 2008 Apr |
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| 7 | 19318350 | Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells. | J Biol Chem | 2009 May 15 |
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| 11 | 23584473 | PKA/Smurf1 signaling-mediated stabilization of Nur77 is required for anticancer drug cisplatin-induced apoptosis. | Oncogene | 2014 Mar 27 |
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| 12 | 23995790 | CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation. | Oncogene | 2014 Jul 10 |
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| 13 | 24238996 | Immunolocalization of Smurf1 in Hirano bodies. | J Neurol Sci | 2014 Jan 15 |
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| 14 | 24287595 | Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. | Nat Commun | 2013 |
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| 15 | 24691097 | Inhibitory role of the KEAP1-NRF2 pathway in TGFβ1-stimulated renal epithelial transition to fibroblastic cells: a modulatory effect on SMAD signaling. | PLoS One | 2014 |
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| 16 | 24821572 | The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis. | Nat Commun | 2014 May 13 |
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| 17 | 25051198 | Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2. | Int J Oncol | 2014 Oct |
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| 18 | 25249323 | ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundance. | Nat Commun | 2014 Sep 24 |
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| 19 | 26004137 | CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. | Cell Signal | 2015 Sep |
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| 20 | 26825171 | RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis. | Cancer Res | 2016 Apr 1 |
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| 21 | 27148690 | Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression. | Cell Death Dis | 2016 May 5 |
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| 22 | 27187737 | Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension. | Am J Respir Cell Mol Biol | 2016 Oct |
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| 23 | 27265199 | Melatonin reversed tumor necrosis factor-alpha-inhibited osteogenesis of human mesenchymal stem cells by stabilizing SMAD1 protein. | J Pineal Res | 2016 Oct |
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| 24 | 28063214 | Reciprocal regulation between βTrCP and Smurf1 suppresses proliferative capacity of liver cancer cells. | J Cell Physiol | 2017 Dec |
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| 25 | 28427181 | Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK. | Oncotarget | 2017 May 16 |
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| 26 | 28581524 | Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKIγ. | Oncogene | 2017 Oct 12 |
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| 27 | 28731194 | SMURF1 promotes the proliferation, migration and invasion of gastric cancer cells. | Oncol Rep | 2017 Sep |
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| 28 | 28847510 | AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation. | Biochim Biophys Acta Mol Cell Res | 2017 Dec |
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| 29 | 29433542 | SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells. | J Exp Clin Cancer Res | 2018 Feb 12 |
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| 30 | 29565736 | Smad ubiquitylation regulatory factor 1 promotes LIM-homeobox gene 9 degradation and represses testosterone production in Leydig cells. | FASEB J | 2018 Sep |
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| 31 | 29753111 | IRAK2 counterbalances oncogenic Smurf1 in colon cancer cells by dictating ER stress. | Cell Signal | 2018 Aug |
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| 32 | 29942010 | Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. | Nat Commun | 2018 Jun 25 |
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| 34 | 30244169 | USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis. | Cell Signal | 2019 Jan |
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| 35 | 30335548 | VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation. | FASEB J | 2019 Feb |
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| 36 | 30395943 | Role of SMURF1 ubiquitin ligase in BMP receptor trafficking and signaling. | Cell Signal | 2019 Feb |
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| 37 | 30566427 | Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis. | PLoS Biol | 2018 Dec |
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| 38 | 30672020 | Deletion of SMURF 1 represses ovarian cancer invasion and EMT by modulating the DAB2IP/AKT/Skp2 feedback loop. | J Cell Biochem | 2019 Jun |
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| 39 | 30686098 | Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth. | Autophagy | 2019 Jul |
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| 40 | 30720112 | Upregulation of microRNA‑194‑5p inhibits hypopharyngeal carcinoma cell proliferation, migration and invasion by targeting SMURF1 via the mTOR signaling pathway. | Int J Oncol | 2019 Apr |
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| 41 | 31140729 | Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF-α-Smurf1-Akt-mTOR-P70S6K pathway. | J Cell Mol Med | 2019 Aug |
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| 42 | 31571913 | MicroRNA-424 regulates cisplatin resistance of gastric cancer by targeting SMURF1 based on GEO database and primary validation in human gastric cancer tissues. | Onco Targets Ther | 2019 |
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| 43 | 31623230 | Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance. | Cells | 2019 Oct 16 |
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| 44 | 32033048 | Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1. | Biomolecules | 2020 Feb 4 |
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| 45 | 32512228 | Low Expression of Smurf1 Enhances the Chemosensitivity of Human Colorectal Cancer to Gemcitabine and Cisplatin in Patient-Derived Xenograft Models. | Transl Oncol | 2020 Sep |
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| 46 | 32683298 | Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1. | Int Immunopharmacol | 2020 Oct |
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| 47 | 32737433 | Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation. | Oncogene | 2020 Sep |
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| 48 | 34452242 | Effective Osteogenic Priming of Mesenchymal Stem Cells through LNA-ASOs-Mediated <i>Sfrp1</i> Gene Silencing. | Pharmaceutics | 2021 Aug 17 |
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