transcription factor 7 like 2, T cell specific, HMG box ; Mus musculus






33 Article(s)
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1 19125404 Expression and molecular diversity of Tcf7l2 in the developing murine cerebellum and brain. J Neurosci Res 2009 May 15 1
2 19409202 Molecular development of the lateral geniculate nucleus in the absence of retinal waves during the time of retinal axon eye-specific segregation. Neuroscience 2009 Apr 10 1
3 21430081 Celecoxib and 2,5-dimethyl-celecoxib prevent cardiac remodeling inhibiting Akt-mediated signal transduction in an inherited dilated cardiomyopathy mouse model. J Pharmacol Exp Ther 2011 Jul 2
4 21673050 Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. Genome Res 2011 Sep 3
5 22719219 Reduction in Tcf7l2 expression decreases diabetic susceptibility in mice. Int J Biol Sci 2012 4
6 22967502 The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis. Am J Physiol Endocrinol Metab 2012 Nov 1 2
7 23028378 TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver. PLoS Genet 2012 Sep 6
8 23434931 TCF7L2 variation and proliferative diabetic retinopathy. Diabetes 2013 Jul 2
9 24035868 Malondialdehyde regulates glucose-stimulated insulin secretion in murine islets via TCF7L2-dependent Wnt signaling pathway. Mol Cell Endocrinol 2014 Jan 25 2
10 24317852 TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass. Diabetologia 2014 Mar 1
11 25178657 5-Fluorouracil causes severe CNS demyelination by disruption of TCF7L2/HDAC1/HDAC2 complex in adolescent mice. Toxicology 2014 Nov 5 7
12 25355422 Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass. Hum Mol Genet 2015 Mar 1 1
13 25398947 Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice. Hum Mol Genet 2015 Mar 15 2
14 25830097 The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis. Mol Metab 2015 Apr 2
15 25950476 Geniposide promotes beta-cell regeneration and survival through regulating β-catenin/TCF7L2 pathway. Cell Death Dis 2015 May 7 6
16 27108846 TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis. Sci Rep 2016 Apr 25 2
17 28102847 Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2. Cell Death Dis 2017 Jan 19 3
18 28343277 Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice. Diabetologia 2017 Jun 2
19 29246974 Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner. Diabetes 2018 Mar 2
20 29713286 The Wnt Signaling Pathway Effector TCF7L2 Mediates Olanzapine-Induced Weight Gain and Insulin Resistance. Front Pharmacol 2018 6
21 29967064 Transcription factor-7-like 2 (<i>TCF7L2</i>) gene acts downstream of the <i>Lkb1</i>/<i>Stk11</i> kinase to control mTOR signaling, β cell growth, and insulin secretion. J Biol Chem 2018 Sep 7 1
22 30398926 Coordinated <i>Tcf7l2</i> regulation in a mouse model implicates Wnt signaling in fetal alcohol spectrum disorders. Biochem Cell Biol 2019 Aug 3
23 30948248 Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism. Mol Metab 2019 Jun 3
24 31619789 Habenular TCF7L2 links nicotine addiction to diabetes. Nature 2019 Oct 1
25 31864766 Corrigendum to "5-Fluorouracil causes severe CNS demyelination by disruption of TCF7L2/HDAC1/HDAC2 complex in adolescent mice" [Toxicology 325 (2014) 144-150]. Toxicology 2020 Jan 30 1
26 31969494 Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway. Aging (Albany NY) 2020 Jan 22 1
27 32739175 Artesunate inhibits atherosclerosis by upregulating vascular smooth muscle cells-derived LPL expression via the KLF2/NRF2/TCF7L2 pathway. Eur J Pharmacol 2020 Oct 5 1
28 32910904 A High-Throughput Genome-Integrated Assay Reveals Spatial Dependencies Governing Tcf7l2 Binding. Cell Syst 2020 Sep 23 1
29 33068125 Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice. Diabetologia 2021 Jan 1
30 33479193 MicroRNA-194: a novel regulator of glucagon-like peptide-1 synthesis in intestinal L cells. Cell Death Dis 2021 Jan 21 1
31 34229476 Estrogen-Wnt signaling cascade regulates expression of hepatic fibroblast growth factor 21. Am J Physiol Endocrinol Metab 2021 Aug 1 2
32 35133032 TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. FASEB J 2022 Mar 2
33 35489221 Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis. J Neuroimmunol 2022 Jun 15 1