adenosine A2b receptor ; Homo sapiens






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1 7603451 Production and characterization of multiple antigenic peptide antibodies to the adenosine A2b receptor. Mol Pharmacol 1995 Jun 1
2 15239649 New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine. J Med Chem 2004 Jul 15 2
3 16821798 A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists. J Med Chem 2006 Jul 13 2
4 17077318 ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor. J Pharmacol Exp Ther 2007 Feb 1
5 17329874 Synthesis and evaluation of adenosine antagonist activity of a series of [1,2,4]triazolo[1,5-c]quinazolines. Chem Pharm Bull (Tokyo) 2007 Mar 3
6 19253308 New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC. Inflamm Bowel Dis 2009 Jul 1
7 19757091 Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor. J Comput Aided Mol Des 2009 Nov 1
8 20619442 Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells. Hum Pathol 2010 Nov 1
9 21586359 Interplay of hypoxia and A2B adenosine receptors in tissue protection. Adv Pharmacol 2011 3
10 21620804 The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function. Biochem Pharmacol 2011 Aug 15 1
11 22634345 Adenosine signaling in normal and sickle erythrocytes and beyond. Microbes Infect 2012 Aug 1
12 22682496 Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action. Arthritis Res Ther 2012 Jun 8 2
13 23263788 Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease. J Mol Med (Berl) 2013 Feb 1
14 23540714 Attenuating myocardial ischemia by targeting A2B adenosine receptors. Trends Mol Med 2013 Jun 3
15 23584256 Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension. Circ Res 2013 May 24 3
16 23638125 The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT) synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease. PLoS One 2013 2
17 23956030 The elevated gene expression level of the A(2B) adenosine receptor is associated with hyperglycemia in women with gestational diabetes mellitus. Diabetes Metab Res Rev 2014 Jan 3
18 24090420 Quantitative insights towards the design of potent deazaxanthine antagonists of adenosine 2B receptors. J Enzyme Inhib Med Chem 2014 Aug 2
19 24589267 The role of adenosine signaling in sickle cell therapeutics. Hematol Oncol Clin North Am 2014 Apr 1
20 24678970 The effects of adenosine A2B receptor inhibition on VEGF and nitric oxide axis-mediated renal function in diabetic nephropathy. Ren Fail 2014 Jul 2
21 25542373 Novel heteroaryl phosphonicdiamides PTPs inhibitors as anti-hyperglycemic agents. Daru 2014 Dec 27 1
22 27479139 Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma. PLoS One 2016 2
23 27705752 SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. Cell Signal 2016 Dec 1
24 28169986 Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun 2017 Feb 7 1
25 28344125 Capadenoson, a clinically trialed partial adenosine A<sub>1</sub> receptor agonist, can stimulate adenosine A<sub>2B</sub> receptor biased agonism. Biochem Pharmacol 2017 Jul 1 1
26 28598776 Expression of the genes facilitating methotrexate action within subcutaneous rheumatoid nodules. Clin Exp Rheumatol 2017 Nov-Dec 1
27 28701304 HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis. FASEB J 2017 Nov 2
28 29454963 Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 2018 Mar 11 1
29 29525433 The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A<sub>2B</sub> receptor. Eur J Med Chem 2018 Apr 25 2
30 29891411 Understanding the Role of Adenosine Receptors in the Myofibroblast Transformation in Peyronie's Disease. J Sex Med 2018 Jul 1
31 30429458 MiR-27b regulates podocyte survival through targeting adenosine receptor 2B in podocytes from non-human primate. Cell Death Dis 2018 Nov 14 2
32 30471466 NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing. Cell Signal 2019 Feb 1
33 31036697 Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema. Dis Model Mech 2019 May 15 1
34 31203399 Baseline adenosine receptor mRNA expression in blood as predictor of response to methotrexate therapy in patients with rheumatoid arthritis. Rheumatol Int 2019 Aug 1
35 31278195 Erythrocyte Adenosine A2B Receptor-Mediated AMPK Activation: A Missing Component Counteracting CKD by Promoting Oxygen Delivery. J Am Soc Nephrol 2019 Aug 3
36 31494223 Differential role of adenosine signaling cascade in acute and chronic pain. Neurosci Lett 2019 Nov 1 1
37 31802389 Targeting adenosinergic pathway enhances the anti-tumor efficacy of sorafenib in hepatocellular carcinoma. Hepatol Int 2020 Jan 1
38 31846065 Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells. Int J Cancer 2020 Jul 1 2
39 32141895 Erythrocyte adaptive metabolic reprogramming under physiological and pathological hypoxia. Curr Opin Hematol 2020 May 4
40 32294028 A Role for the Adenosine ADORA2B Receptor in Midazolam Induced Cognitive Dysfunction. Curr Pharm Des 2020 1
41 33584346 Co-inhibition of CD73 and ADORA2B Improves Long-Term Cigarette Smoke Induced Lung Injury. Front Physiol 2021 2
42 34314252 Response to Hypoxia in Cognitive Decline. Rejuvenation Res 2021 Aug 1
43 35203352 Identification of Dysregulated Expression of G Protein Coupled Receptors in Endocrine Tumors by Bioinformatics Analysis: Potential Drug Targets? Cells 2022 Feb 17 1