Title : HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.

Pub. Date : 2017 Nov

PMID : 28701304






2 Functional Relationships(s)
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1 Extracellular accumulation of adenosine and subsequent activation of the ADORA2B receptor play important roles in regulating inflammation and fibrosis in IPF. Adenosine adenosine A2b receptor Homo sapiens
2 Additionally, alternatively activated macrophages (AAMs) expressing ADORA2B have been implicated in mediating adenosine"s effects in IPF. Adenosine adenosine A2b receptor Homo sapiens