squalene monooxygenase ; Saccharomyces cerevisiae S288C






39 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 7791529 Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. Lipids 1995 Mar 1
2 8771716 ERG1, encoding squalene epoxidase, is located on the right arm of chromosome VII of Saccharomyces cerevisiae. Yeast 1996 May 1
3 9450962 Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particles. Mol Biol Cell 1998 Feb 1
4 9811880 Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis. Proc Natl Acad Sci U S A 1998 Nov 10 1
5 11179957 A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae. Eur J Biochem 2001 Feb 7
6 11298754 A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. Eur J Biochem 2001 Apr 1
7 12963042 Terbinafine resistance in a pleiotropic yeast mutant is caused by a single point mutation in the ERG1 gene. Biochem Biophys Res Commun 2003 Sep 26 7
8 14554200 Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. FEMS Yeast Res 2003 Oct 2
9 14638499 Molecular mechanism of terbinafine resistance in Saccharomyces cerevisiae. Antimicrob Agents Chemother 2003 Dec 4
10 15155725 A yeast strain lacking lipid particles bears a defect in ergosterol formation. J Biol Chem 2004 Jul 23 1
11 15157604 Targeting of proteins involved in sterol biosynthesis to lipid particles of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 2004 May 27 1
12 15215098 Candida glabrata erg1 mutant with increased sensitivity to azoles and to low oxygen tension. Antimicrob Agents Chemother 2004 Jul 4
13 16246080 Single amino acid exchanges in FAD-binding domains of squalene epoxidase of Saccharomyces cerevisiae lead to either loss of functionality or terbinafine sensitivity. Biochem Soc Trans 2005 Nov 5
14 17043127 Characterization of squalene epoxidase of Saccharomyces cerevisiae by applying terbinafine-sensitive variants. Antimicrob Agents Chemother 2007 Jan 8
15 17569082 Expression of the gene for sterol-biosynthesis enzyme squalene epoxidase in parenchyma cells of the oil plant, Euphorbia tirucalli. Planta 2007 Oct 2
16 19175415 The influence of yeast oxygenation prior to brewery fermentation on yeast metabolism and the oxidative stress response. FEMS Yeast Res 2009 Mar 2
17 21075079 A role for MGA2, but not SPT23, in activation of transcription of ERG1 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 2010 Dec 17 1
18 23898401 Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4. Elife 2013 Jul 23 1
19 24119181 Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae. FEMS Yeast Res 2014 Mar 7
20 25298782 Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock. Biotechnol Biofuels 2014 11
21 25475753 Genomic reconstruction to improve bioethanol and ergosterol production of industrial yeast Saccharomyces cerevisiae. J Ind Microbiol Biotechnol 2015 Feb 1
22 25764133 Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes. PLoS One 2015 1
23 25788404 Building terpene production platforms in yeast. Biotechnol Bioeng 2015 Sep 1
24 25830359 Isolation and characterization of two squalene epoxidase genes from Botryococcus braunii, race B. PLoS One 2015 1
25 25889168 Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae. Microb Cell Fact 2015 Mar 18 1
26 29471044 Engineered protein degradation of farnesyl pyrophosphate synthase is an effective regulatory mechanism to increase monoterpene production in Saccharomyces cerevisiae. Metab Eng 2018 May 1
27 29594560 Rate-limiting steps in the Saccharomyces cerevisiae ergosterol pathway: towards improved ergosta-5,7-dien-3β-ol accumulation by metabolic engineering. World J Microbiol Biotechnol 2018 Mar 28 2
28 30016654 Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast. Metab Eng 2018 Sep 2
29 30450126 Changes in lipid metabolism convey acid tolerance in <i>Saccharomyces cerevisiae</i>. Biotechnol Biofuels 2018 4
30 31606910 Engineering of Saccharomyces cerevisiae for the production of (+)-ambrein. Yeast 2020 Jan 5
31 32024107 Self-Redirection of Metabolic Flux Toward Squalene and Ethanol Pathways by Engineered Yeast. Metabolites 2020 Feb 1 1
32 32561581 Squalene-Tetrahymanol Cyclase Expression Enables Sterol-Independent Growth of Saccharomyces cerevisiae. Appl Environ Microbiol 2020 Aug 18 2
33 33524398 Deubiquitinase Ubp3 enhances the proteasomal degradation of key enzymes in sterol homeostasis. J Biol Chem 2021 Jan-Jun 2
34 33648022 Adaptive evolution of engineered yeast for squalene production improvement and its genome-wide analysis. Yeast 2021 Jul 1
35 34093477 Compartmentalized Reconstitution of Post-<i>s</i>qualene Pathway for 7-Dehydrocholesterol Overproduction in <i>Saccharomyces cerevisiae</i>. Front Microbiol 2021 2
36 34662105 Engineering of cis-Element in <i>Saccharomyces cerevisiae</i> for Efficient Accumulation of Value-Added Compound Squalene via Downregulation of the Downstream Metabolic Flux. J Agric Food Chem 2021 Oct 27 2
37 35198543 Metabolic Engineering of <i>Saccharomyces cerevisiae</i> for High-Level Friedelin <i>via</i> Genetic Manipulation. Front Bioeng Biotechnol 2022 1
38 35531990 Enhancing fluxes through the mevalonate pathway in Saccharomyces cerevisiae by engineering the HMGR and β-alanine metabolism. Microb Biotechnol 2022 May 9 1
39 35606304 Enhanced squalene production by modulation of pathways consuming squalene and its precursor. J Biosci Bioeng 2022 Jul 4