guanine nucleotide binding protein, alpha O ; Mus musculus






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1 1848817 Treatment of intact striatal neurones with cholera toxin or 8-bromoadenosine 3',5'-(cyclic)phosphate decreases the ability of pertussis toxin to ADP-ribosylate the alpha-subunits of inhibitory and other guanine-nucleotide-binding regulatory proteins, Gi and Go. Evidence for two distinct mechanisms. Eur J Biochem 1991 Mar 14 3
2 1906458 Metabolism of two Go alpha isoforms in neuronal cells during differentiation. J Biol Chem 1991 Jul 15 2
3 1963397 In vitro effects of 17 beta-oestradiol on the sensitivity of receptors coupled to adenylate cyclase on striatal neurons in primary culture. Ciba Found Symp 1990 3
4 2107277 Neuroblastoma differentiation involves the expression of two isoforms of the alpha-subunit of Go. J Neurochem 1990 Apr 3
5 2118945 Pretreatment of mouse striatal neurons in primary culture with 17 beta-estradiol enhances the pertussis toxin-catalyzed ADP-ribosylation of G alpha o,i protein subunits. J Neurochem 1990 Oct 5
6 2494307 Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes. J Neurosci 1989 Mar 2
7 2504885 The GTP-binding proteins, Go and Gi2, of neural cloned cells and their changes during differentiation. J Neurochem 1989 Oct 1
8 3123616 Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells. J Neurosci 1988 Feb 1
9 3128978 GTP analogues cause release of the alpha subunit of the GTP binding protein, GO, from the plasma membrane of NG108-15 cells. Biochem Biophys Res Commun 1988 Apr 15 1
10 3131483 Chronic membrane depolarization regulates the level of the guanine nucleotide binding protein Go alpha in cultured neuronal cells. J Neurochem 1988 Jun 1
11 7748334 Involvement of adenosine in ethanol-induced changes in G-protein expression in NG108-15 cells? Alcohol Alcohol Suppl 1993 2
12 8095554 D2-dopaminergic agonist quinpirole and 8-bromo-cAMP have opposite effects on Go alpha GTP-binding protein mRNA without changing D2 dopamine receptor mRNA levels in striatal neurones in primary culture. J Recept Res 1993 6
13 8381506 Ethanol differentially regulates guanine nucleotide-binding protein alpha subunit expression in NG108-15 cells independently of extracellular adenosine. Mol Pharmacol 1993 Feb 2
14 8700136 Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits. Mol Pharmacol 1996 Aug 1
15 9279808 Different G proteins mediate somatostatin-induced inward rectifier K+ currents in murine brain and endocrine cells. J Physiol 1997 Aug 1 1
16 10196137 Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor. J Biol Chem 1999 Apr 16 5
17 10559239 Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function. J Biol Chem 1999 Nov 19 3
18 10588714 Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat. Proc Natl Acad Sci U S A 1999 Dec 7 2
19 10608281 Myr+-Gi2 alpha and Go alpha subunits restore the efficacy of opioids, clonidine and neurotensin giving rise to antinociception in G-protein knock-down mice. Neuropharmacology 1999 Dec 1
20 10669512 Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). J Neurophysiol 2000 Feb 7
21 10883729 In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation. Life Sci 2000 May 19 1
22 10924811 Differential effects of antisense oligodeoxynucleotides directed against g(zalpha) and g(oalpha) on antinociception produced by spinal opioid and alpha(2) adrenergic receptor agonists. Pain 2000 Aug 3
23 15585744 Functional characterization of Galphao signaling through G protein-regulated inducer of neurite outgrowth 1. Mol Pharmacol 2005 Mar 1
24 15657046 Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII. J Biol Chem 2005 Mar 25 2
25 16325780 Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors. Biochem Biophys Res Commun 2006 Jan 13 1
26 18584336 Transcriptomic and proteomic analyses of mouse cerebellum reveals alterations in RasGRF1 expression following in vivo chronic treatment with delta 9-tetrahydrocannabinol. J Mol Neurosci 2009 Feb 1
27 19460419 Gnao1 (G alphaO protein) is a likely genetic contributor to variation in physical dependence on opioids in mice. Neuroscience 2009 Sep 15 3
28 20622165 Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells. Diabetes 2010 Oct 1
29 21317923 Molecular basis of a novel oncogenic mutation in GNAO1. Oncogene 2011 Jun 9 1
30 21654736 μ-Opioid receptor coupling to Gα(o) plays an important role in opioid antinociception. Neuropsychopharmacology 2011 Sep 4
31 23077035 Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. J Neurosci 2012 Oct 17 1
32 23224819 Palmitoylcarnitine affects localization of growth associated protein GAP-43 in plasma membrane subdomains and its interaction with Gα(o) in neuroblastoma NB-2a cells. Neurochem Res 2013 Mar 2
33 23467353 Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein. J Neurosci 2013 Mar 6 2
34 27065801 Identification of a Novel Gnao-Mediated Alternate Olfactory Signaling Pathway in Murine OSNs. Front Cell Neurosci 2016 1
35 27867358 Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex. Front Pharmacol 2016 1
36 28971229 Role of the guanine nucleotide binding protein, Gα<sub>o,</sub> in the development of morphine tolerance and dependence. Psychopharmacology (Berl) 2018 Jan 8
37 29437250 Melatonin-mediated inhibition of Cav3.2 T-type Ca<sup>2+</sup> channels induces sensory neuronal hypoexcitability through the novel protein kinase C-eta isoform. J Pineal Res 2018 May 1
38 30682176 Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes. PLoS One 2019 1
39 31907305 Mice with <i>GNAO1</i> R209H Movement Disorder Variant Display Hyperlocomotion Alleviated by Risperidone. J Pharmacol Exp Ther 2020 Apr 2
40 32329702 Zidovudine Glycosylation by Filamentous Fungi Leads to a Better Redox Stability and Improved Cytotoxicity in B16F10 Murine Melanoma Cells. Anticancer Agents Med Chem 2020 2
41 33857254 Neuromedin U uses Gαi2 and Gαo to suppress glucose-stimulated Ca2+ signaling and insulin secretion in pancreatic β cells. PLoS One 2021 5
42 34248508 Cellular Diversity and Differential Subcellular Localization of the G-Protein G<sub>αo</sub> Subunit in the Mouse Cerebellum. Front Neuroanat 2021 1