| 1 | 8325642 | A genetic analysis of the Werner syndrome region on human chromosome 8p. | Genomics | 1993 Jun |
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| 2 | 9611231 | Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. | Nucleic Acids Res | 1998 Jun 15 |
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| 3 | 9683536 | Werner helicase is localized to transcriptionally active nucleoli of cycling cells. | Exp Cell Res | 1998 Aug 1 |
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| 4 | 9823331 | Failure to complement abnormal phenotypes of simian virus 40-transformed Werner syndrome cells by introduction of a normal human chromosome 8. | Cancer Res | 1998 Nov 15 |
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| 5 | 9852074 | Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease. | J Biol Chem | 1998 Dec 18 |
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| 6 | 10071186 | Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase. | Hum Genet | 1999 Jan |
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| 7 | 10212265 | Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. | J Biol Chem | 1999 Apr 30 |
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| 8 | 10480367 | Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines. | Hum Genet | 1999 Jul-Aug |
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| 9 | 10811112 | WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts. | Cancer Res | 2000 May 1 |
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| 10 | 10871376 | Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. | Nucleic Acids Res | 2000 Jun 15 |
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| 11 | 11256630 | Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. | EMBO Rep | 2000 Jul |
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| 12 | 11328876 | A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA. | Nucleic Acids Res | 2001 May 1 |
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| 13 | 11380620 | Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. | Genes Cells | 2001 May |
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| 14 | 11389927 | The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. | Mech Ageing Dev | 2001 Aug |
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| 15 | 11427532 | p53 Modulates the exonuclease activity of Werner syndrome protein. | J Biol Chem | 2001 Sep 14 |
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| 16 | 11433031 | The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. | Nucleic Acids Res | 2001 Jul 1 |
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| 17 | 11498731 | A polymorphic variant at the Werner helicase (WRN) gene is associated with bone density, but not spondylosis, in postmenopausal women. | J Bone Miner Metab | 2001 |
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| 18 | 11717307 | DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA. | J Biol Chem | 2002 Feb 8 |
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| 19 | 11956187 | Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase. | J Biol Chem | 2002 Jun 28 |
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| 20 | 11971179 | WRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex. | Oncogene | 2002 Apr 11 |
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| 21 | 11978740 | Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. | FASEB J | 2002 May |
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| 22 | 12384494 | DNA damage-induced translocation of the Werner helicase is regulated by acetylation. | J Biol Chem | 2002 Dec 27 |
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| 23 | 12937274 | DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP. | Mol Biol Cell | 2003 Oct |
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| 24 | 12944467 | Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution. | Mol Cell Biol | 2003 Sep |
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| 25 | 14596914 | Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase. | FEBS Lett | 2003 Nov 6 |
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| 26 | 14612404 | Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage. | Mol Cell Biol | 2003 Dec |
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| 27 | 14612507 | Werner protein stimulates topoisomerase I DNA relaxation activity. | Cancer Res | 2003 Nov 1 |
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| 28 | 15026416 | Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. | J Biol Chem | 2004 May 14 |
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| 29 | 15037256 | Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion. | J Struct Biol | 2004 Apr-May |
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| 30 | 15135730 | The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. | DNA Repair (Amst) | 2004 Jun 3 |
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| 31 | 15149862 | Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-beta-D-arabinofuranosylcytosine and bleomycin. | Exp Cell Res | 2004 Jun 10 |
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| 32 | 15187093 | Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein. | J Biol Chem | 2004 Aug 13 |
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| 33 | 15241474 | Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. | EMBO J | 2004 Jul 21 |
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| 34 | 15256542 | RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases. | Nucleic Acids Res | 2004 |
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| 35 | 15282207 | In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication. | Hum Mol Genet | 2004 Oct 1 |
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| 36 | 15459124 | Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest. | FASEB J | 2004 Dec |
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| 37 | 16087220 | Cellular dynamics and modulation of WRN protein is DNA damage specific. | Mech Ageing Dev | 2005 Nov |
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| 38 | 16098926 | WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus. | Diabetes Res Clin Pract | 2005 Sep |
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| 39 | 16150736 | Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain. | J Biol Chem | 2005 Nov 25 |
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| 40 | 16287861 | Werner protein protects nonproliferating cells from oxidative DNA damage. | Mol Cell Biol | 2005 Dec |
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| 41 | 16362795 | Polymorphisms of the TP53 codon 72 and WRN codon 1367 in individuals from Northern Brazil with gastric adenocarcinoma. | Clin Exp Med | 2005 Dec |
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| 42 | 16380375 | Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A. | J Biol Chem | 2006 Mar 3 |
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| 43 | 16449207 | The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. | Nucleic Acids Res | 2006 |
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| 44 | 16503984 | Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains. | BMC Mol Biol | 2006 Feb 17 |
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| 45 | 16723399 | Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. | Proc Natl Acad Sci U S A | 2006 Jun 6 |
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| 46 | 16728435 | Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity. | Carcinogenesis | 2006 Oct |
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| 47 | 16793395 | Enzymatic mechanism of the WRN helicase/nuclease. | Methods Enzymol | 2006 |
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| 48 | 17173071 | The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage. | Oncogene | 2007 May 31 |
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| 49 | 17224176 | WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups. | Mech Ageing Dev | 2007 Mar |
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| 50 | 17449919 | Increased chromosome instability and accumulation of DNA double-strand breaks in Werner syndrome cells. | J Radiat Res | 2007 May |
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