| 1 | 12700167 | Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy. | Hum Mol Genet | 2003 May 1 |
4 |
| 2 | 15486067 | Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species. | Blood | 2005 Feb 15 |
2 |
| 3 | 15654601 | Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes. | Diabetologia | 2005 Feb |
1 |
| 4 | 18039784 | Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells. | Endocrinology | 2008 Mar |
1 |
| 5 | 18366086 | The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation. | J Cell Physiol | 2008 Aug |
1 |
| 6 | 18672974 | Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs. | Am J Vet Res | 2008 Aug |
1 |
| 7 | 19231960 | Activation of the AKT and mammalian target of rapamycin pathways and the inhibitory effects of rapamycin on those pathways in canine malignant melanoma cell lines. | Am J Vet Res | 2009 Feb |
4 |
| 8 | 22177999 | Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines. | Exp Neurol | 2012 Feb |
2 |
| 9 | 22182476 | Everolimus in combination with cyclosporin a as pre- and posttransplantation immunosuppressive therapy in nonmyeloablative allogeneic hematopoietic stem cell transplantation. | Biol Blood Marrow Transplant | 2012 Jul |
1 |
| 10 | 23128666 | Pleiotropic effects of long-term monotherapy with rosuvastatin in dogs with moderate heart failure. | Cardiology | 2012 |
1 |
| 11 | 25981932 | Anti-tumour effect of metformin in canine mammary gland tumour cells. | Vet J | 2015 Aug |
1 |
| 12 | 26205886 | High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression. | BMC Cancer | 2015 Jul 25 |
4 |
| 13 | 27463366 | Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma. | Pigment Cell Melanoma Res | 2016 Nov |
1 |
| 14 | 28559962 | Icariside II promotes the osteogenic differentiation of canine bone marrow mesenchymal stem cells via the PI3K/AKT/mTOR/S6K1 signaling pathways. | Am J Transl Res | 2017 |
1 |
| 15 | 30011343 | In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma. | PLoS One | 2018 |
1 |
| 16 | 30569877 | Evaluation of Angiogenesis Process after Metformin and LY294002 Treatment in Mammary Tumor. | Anticancer Agents Med Chem | 2019 |
2 |
| 17 | 31273547 | Basic Research in Diabetic Nephropathy Health Care: A study of the Renoprotective Mechanism of Metformin. | J Med Syst | 2019 Jul 4 |
3 |
| 18 | 31955800 | Dysregulated Expression of Phosphorylated Epidermal Growth Factor Receptor and Phosphatase and Tensin Homologue in Canine Cutaneous Papillomas and Squamous Cell Carcinomas. | J Comp Pathol | 2020 Jan |
1 |
| 19 | 33668689 | Proteomics Approach of Rapamycin Anti-Tumoral Effect on Primary and Metastatic Canine Mammary Tumor Cells In Vitro. | Molecules | 2021 Feb 25 |
1 |
| 20 | 33753454 | Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs. | Clin Cancer Res | 2021 Jun 1 |
2 |
| 21 | 34733370 | Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway <i>in vitro</i>. | Oncol Lett | 2021 Dec |
3 |
| 22 | 34895222 | Investigation of the effects of mTOR inhibitors rapamycin and everolimus in combination with carboplatin on canine malignant melanoma cells. | BMC Vet Res | 2021 Dec 11 |
8 |
| 23 | 34975216 | Modulation of mTOR signaling by radiation and rapamycin treatment in canine mast cell cancer cells. | Can J Vet Res | 2022 Jan |
4 |
| 24 | 35088890 | Antitumor activity of the dual PI3K/mTOR inhibitor gedatolisib and the involvement of ABCB1 in gedatolisib resistance in canine tumor cells. | Oncol Rep | 2022 Apr |
1 |