Title : High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression.

Pub. Date : 2015 Jul 25

PMID : 26205886






4 Functional Relationships(s)
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1 Inhibition of the HER-regulated PI3K/mTor pathway using the dual PI3K/mTor inhibitor BEZ235 or the mTor inhibitor Everolimus resulted in reduced cell proliferation. dactolisib mechanistic target of rapamycin kinase Canis lupus familiaris
2 Inhibition of the HER-regulated PI3K/mTor pathway using the dual PI3K/mTor inhibitor BEZ235 or the mTor inhibitor Everolimus resulted in reduced cell proliferation. dactolisib mechanistic target of rapamycin kinase Canis lupus familiaris
3 Inhibition of the HER-regulated PI3K/mTor pathway using the dual PI3K/mTor inhibitor BEZ235 or the mTor inhibitor Everolimus resulted in reduced cell proliferation. dactolisib mechanistic target of rapamycin kinase Canis lupus familiaris
4 Inhibition of the HER-regulated PI3K/mTor pathway using the dual PI3K/mTor inhibitor BEZ235 or the mTor inhibitor Everolimus resulted in reduced cell proliferation. Everolimus mechanistic target of rapamycin kinase Canis lupus familiaris