tumor protein p53 binding protein 1 ; Homo sapiens






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1 8910340 p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition. J Biol Chem 1996 Nov 1 2
2 9989832 Reduced growth rate and transformation phenotype of the prostate cancer cells by an interferon-inducible protein, p202. Oncogene 1999 Jan 21 1
3 11013253 The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression. J Biol Chem 2001 Jan 5 1
4 11331310 Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J Cell Biol 2001 Apr 30 5
5 12697768 Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J Biol Chem 2003 May 30 3
6 15492236 p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder. Cancer Res 2004 Oct 15 2
7 15856006 53BP1 is associated with replication protein A and is required for RPA2 hyperphosphorylation following DNA damage. Oncogene 2005 Aug 18 4
8 16009723 Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J Cell Biol 2005 Jul 18 2
9 16187115 Jun activation domain-binding protein 1 is required for mitotic checkpoint activation via its involvement in hyperphosphorylation of 53BP1. J Cancer Res Clin Oncol 2005 Dec 2
10 16294045 The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity. Cell Cycle 2005 Dec 8
11 16294047 53BP1 oligomerization is independent of its methylation by PRMT1. Cell Cycle 2005 Dec 3
12 16298690 Modulation of DNA-dependent protein kinase activity in chlorambucil-treated cells. Free Radic Biol Med 2005 Dec 15 1
13 16314399 Joint effects of single nucleotide polymorphisms in P53BP1 and p53 on breast cancer risk in a Chinese population. Carcinogenesis 2006 Apr 10
14 16395335 Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J 2006 Jan 11 1
15 16618811 Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 2006 Apr 24 1
16 16945145 Tying the loose ends together in DNA double strand break repair with 53BP1. Cell Div 2006 Aug 31 2
17 17190600 Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006 Dec 29 7
18 17575156 Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res 2007 Jun 15 3
19 17669438 Bystander response in human lymphoblastoid TK6 cells. Mutat Res 2007 Dec 1 1
20 17927872 [Correlation of 53BP1 and p53 polymorphisms to susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]. Ai Zheng 2007 Oct 1
21 18026117 L3MBTL1 recognition of mono- and dimethylated histones. Nat Struct Mol Biol 2007 Dec 1
22 18158901 Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair. Mol Cell 2007 Dec 28 1
23 18645678 Adriamycin induces H2AX phosphorylation in human spermatozoa. Asian J Androl 2008 Sep 1
24 18839414 Microwaves from UMTS/GSM mobile phones induce long-lasting inhibition of 53BP1/gamma-H2AX DNA repair foci in human lymphocytes. Bioelectromagnetics 2009 Feb 1
25 18840612 Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. J Biol Chem 2008 Dec 12 3
26 18848520 SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint. Biochem Biophys Res Commun 2008 Dec 5 1
27 19176521 Protein phosphatase 5 regulates the function of 53BP1 after neocarzinostatin-induced DNA damage. J Biol Chem 2009 Apr 10 5
28 19203579 RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009 Feb 6 1
29 19228710 RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1. Nucleic Acids Res 2009 Apr 4
30 19557000 Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks. EMBO Rep 2009 Aug 2
31 19621083 Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response. PLoS One 2009 Jul 21 1
32 19650866 Analysis of ionizing radiation-induced DNA damage and repair in three-dimensional human skin model system. Exp Dermatol 2010 Aug 1
33 19656881 Functional interaction between Epstein-Barr virus replication protein Zta and host DNA damage response protein 53BP1. J Virol 2009 Nov 4
34 19876065 53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope. Cell Death Differ 2010 May 1
35 19915695 Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs. Korean J Physiol Pharmacol 2009 Oct 1
36 20080757 The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proc Natl Acad Sci U S A 2010 Jan 12 1
37 20307547 Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J Mol Biol 2010 May 14 2
38 20372852 Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population. Oncol Rep 2010 May 5
39 20596616 Expression of 53BP1 as a cisplatin-resistant marker in patients with lung adenocarcinomas. Oncol Rep 2010 Aug 2
40 20660387 In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer. J Nucl Med 2010 Aug 3
41 20708982 Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate. DNA Repair (Amst) 2010 Oct 5 1
42 20876283 The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair. J Cell Biol 2010 Oct 4 1
43 20921134 BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J Cell Biol 2010 Oct 4 1
44 20973777 Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein. Br J Pharmacol 2011 Feb 3
45 21036673 The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax. DNA Repair (Amst) 2010 Dec 10 1
46 21271785 Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions. Int J Radiat Biol 2011 Jul 1
47 21285347 MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor. J Biol Chem 2011 Apr 8 1
48 21293379 MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 2011 Feb 3 6
49 21444690 Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol 2011 Apr 4 1
50 21549309 Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. Mol Cell 2011 May 6 2