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| 2 | 7916985 | Use of representational difference analysis for the identification of mdm2 oncogene amplification in diethylstilbestrol-induced murine uterine adenocarcinomas. | Mol Carcinog | 1994 Sep |
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| 3 | 8649767 | Analysis of the proportion of p53 bound to mdm-2 in cells with defined growth characteristics. | Oncogene | 1996 Jun 6 |
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| 4 | 8761295 | Induction of apoptosis by tamoxifen-activation of a p53-estrogen receptor fusion protein expressed in E1A and T24 H-ras transformed p53-/- mouse embryo fibroblasts. | Oncogene | 1996 Aug 15 |
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| 5 | 9548451 | Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma. | Jpn J Cancer Res | 1998 Feb |
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| 6 | 9738462 | p53 and the ribosomal protein L5 participate in high molecular mass complex formation with protein kinase CK2 in murine teratocarcinoma cell line F9 after serum stimulation and cisplatin treatment. | FEBS Lett | 1998 Aug 28 |
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| 7 | 10222137 | An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs. | Exp Cell Res | 1999 May 1 |
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| 8 | 10404639 | Determination of mRNA, and protein levels of p53, MDM2 and protein kinase CK2 subunits in F9 cells after treatment with the apoptosis-inducing drugs cisplatin and carboplatin. | Int J Biochem Cell Biol | 1999 Jun |
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| 9 | 10432310 | Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers. | Biochem J | 1999 Aug 15 |
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| 10 | 10492400 | Constitutive mdmx expression during cell growth, differentiation, and DNA damage. | DNA Cell Biol | 1999 Sep |
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| 11 | 10493945 | MDM2 oncogene as a target for cancer therapy: An antisense approach. | Int J Oncol | 1999 Oct |
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| 12 | 10614665 | The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells. | Endocrinology | 2000 Jan |
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| 13 | 10643981 | Inactivation of p53 and retinoblastoma family pathways in canine osteosarcoma cell lines. | Vet Pathol | 2000 Jan |
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| 14 | 10710310 | DNA damage-induced activation of p53 by the checkpoint kinase Chk2. | Science | 2000 Mar 10 |
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| 15 | 10713175 | Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex. | Mol Cell Biol | 2000 Apr |
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| 16 | 10747924 | Protection of renal inner medullary epithelial cells from apoptosis by hypertonic stress-induced p53 activation. | J Biol Chem | 2000 Jun 16 |
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| 17 | 10856296 | DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. | J Biol Chem | 2000 Aug 25 |
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| 18 | 10894886 | Genetic analysis of Raf1, Mdm2, c-Myc, Cdc25a and Cdc25b proto-oncogenes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced lymphomas in B6C3F1 mice. | Mutat Res | 2000 Jul 20 |
2 |
| 19 | 11035041 | Ionizing radiation down-regulates p53 protein in primary Egr-1-/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. | J Biol Chem | 2001 Feb 2 |
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| 20 | 11237699 | Purification of a fragment of MDM2 for production of polyclonal antisera. | Protein Expr Purif | 2001 Mar |
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| 21 | 11284721 | Phosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cells. | Biochem J | 2001 Apr 15 |
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| 22 | 11359766 | Cyclin a-CDK phosphorylation regulates MDM2 protein interactions. | J Biol Chem | 2001 Aug 10 |
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| 23 | 11867628 | p53 Activation by nitric oxide involves down-regulation of Mdm2. | J Biol Chem | 2002 May 3 |
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| 24 | 11894120 | Antisense anti-MDM2 mixed-backbone oligonucleotides enhance therapeutic efficacy of topoisomerase I inhibitor irinotecan in nude mice bearing human cancer xenografts: In vivo activity and mechanisms. | Int J Oncol | 2002 Apr |
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| 25 | 12135628 | Cadmium affects genes involved in growth regulation during two-stage transformation of Balb/3T3 cells. | Toxicology | 2002 Aug 15 |
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| 26 | 12589031 | Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway. | Mol Cancer Ther | 2003 Feb |
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| 27 | 12605714 | Hepatocarcinogenic potential of the glucocorticoid antagonist RU486 in B6C3F1 mice: effect on apoptosis, expression of oncogenes and the tumor suppressor gene p53. | Mol Cancer | 2003 Jan 3 |
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| 28 | 12881704 | Rescue of mutant p53 transcription function by ellipticine. | Oncogene | 2003 Jul 17 |
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| 29 | 12894226 | Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. | Oncogene | 2003 Jul 31 |
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| 30 | 12955074 | Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase. | Oncogene | 2003 Sep 4 |
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| 31 | 14625023 | Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations. | Neurosci Lett | 2003 Dec 11 |
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| 32 | 14766674 | Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice. | Am J Physiol Heart Circ Physiol | 2004 Mar |
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| 33 | 15024700 | A truncated isoform of the PP2A B56gamma regulatory subunit reduces irradiation-induced Mdm2 phosphorylation and could contribute to metastatic melanoma cell radioresistance. | Histol Histopathol | 2004 Apr |
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| 34 | 15342939 | Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. | Stem Cells | 2004 |
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| 35 | 15385570 | Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha. | J Biol Chem | 2004 Dec 17 |
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| 36 | 15610030 | Protein kinase CK1delta phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover. | Biochemistry | 2004 Dec 28 |
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| 37 | 15908939 | Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. | Nat Biotechnol | 2005 Jun |
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| 38 | 16014563 | MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy. | Blood | 2005 Nov 1 |
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| 39 | 16180010 | Involvement of the extracellular signal-regulated protein kinase pathway in phosphorylation of p53 protein and exerting cytotoxicity in human neuroblastoma cells (SH-SY5Y) exposed to acrylamide. | Arch Toxicol | 2006 Mar |
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| 40 | 16208531 | Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expression. | Virchows Arch | 2006 Jan |
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| 41 | 16244358 | Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase. | Carcinogenesis | 2006 Mar |
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| 42 | 16335531 | Phosphorylation of the acidic domain of Mdm2 by protein kinase CK2. | Mol Cell Biochem | 2005 Jun |
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| 43 | 16339144 | Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase. | J Biol Chem | 2006 Feb 10 |
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| 44 | 16616333 | A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network. | Cancer Cell | 2006 Apr |
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| 45 | 16789731 | Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy. | J Med Chem | 2006 Jun 29 |
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| 46 | 16914427 | Uteroplacental insufficiency increases p53 phosphorylation without triggering the p53-MDM2 functional circuit response in the IUGR rat kidney. | Am J Physiol Regul Integr Comp Physiol | 2006 Aug |
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| 47 | 16949053 | Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors. | Biochem Pharmacol | 2006 Oct 16 |
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| 48 | 16982679 | MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. | Mol Cell Biol | 2006 Dec |
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| 49 | 17215852 | Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts. | Leukemia | 2007 Mar |
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| 50 | 17306348 | An inhibitory effect on cell proliferation by blockage of the MAPK/estrogen receptor/MDM2 signal pathway in gynecologic cancer. | Gynecol Oncol | 2007 May |
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