Title : Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.

Pub. Date : 2007 Mar

PMID : 17215852






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We also demonstrate that wortmannin-dependent PI3K/Akt inhibition upregulated p53 protein levels in most AML cases, and this correlated with diminished MRP1 expression and enhanced phosphorylation of murine double minute 2 (MDM2). Wortmannin transformed mouse 3T3 cell double minute 2 Mus musculus