| 1 | 17028578 | Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. | Nat Cell Biol | 2006 Nov |
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| 2 | 17049657 | Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. | Neurosci Res | 2006 Dec |
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| 3 | 17130845 | Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. | Oncogene | 2007 Apr 12 |
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| 4 | 17297610 | Low LATS2 mRNA level can predict favorable response to epirubicin plus cyclophosphamide, but not to docetaxel, in breast cancers. | J Cancer Res Clin Oncol | 2007 Aug |
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| 5 | 18328708 | MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. | Curr Biol | 2008 Mar 11 |
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| 6 | 20841485 | Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway. | Cancer Res | 2010 Nov 1 |
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| 7 | 22641346 | LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. | J Cell Biol | 2012 May 28 |
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| 8 | 22863277 | Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. | Cell | 2012 Aug 17 |
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| 9 | 24101513 | Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases. | Proc Natl Acad Sci U S A | 2013 Oct 22 |
2 |
| 10 | 24929361 | Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling. | Nat Cell Biol | 2014 Jul |
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| 11 | 25180175 | Phosphoproteomic analysis of gossypol-induced apoptosis in ovarian cancer cell line, HOC1a. | Biomed Res Int | 2014 |
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| 12 | 25270913 | Methylation‑associated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma. | Int J Oncol | 2014 Dec |
8 |
| 13 | 25712415 | 17-AAG suppresses growth and invasion of lung adenocarcinoma cells via regulation of the LATS1/YAP pathway. | J Cell Mol Med | 2015 Mar |
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| 14 | 25723520 | LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. | PLoS One | 2015 |
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| 15 | 27052725 | The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis. | Cell Cycle | 2016 May 18 |
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| 16 | 27119551 | HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension. | Am J Respir Crit Care Med | 2016 Oct 1 |
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| 17 | 27206784 | Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance. | Chin J Cancer | 2016 May 20 |
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| 18 | 27759563 | Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis. | Elife | 2016 Oct 19 |
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| 19 | 28232662 | Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis. | Exp Mol Med | 2017 Feb 24 |
3 |
| 20 | 28259899 | LATS1 suppresses proliferation and invasion of cervical cancer. | Mol Med Rep | 2017 Apr |
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| 21 | 28754671 | Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1. | Cancer Res | 2017 Sep 15 |
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| 22 | 28886238 | SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes. | FEBS J | 2017 Nov |
2 |
| 23 | 28972170 | β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin. | J Biol Chem | 2017 Nov 24 |
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| 24 | 29168038 | Ovarian serous carcinomas acquire cisplatin resistance and increased invasion through downregulation of the high-temperature-required protein A2 (HtrA2), following repeated treatment with cisplatin. | Med Oncol | 2017 Nov 22 |
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| 25 | 29689192 | Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. | Dev Cell | 2018 Apr 23 |
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| 26 | 29758456 | GPER/Hippo-YAP signal is involved in Bisphenol S induced migration of triple negative breast cancer (TNBC) cells. | J Hazard Mater | 2018 Aug 5 |
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| 27 | 29903769 | YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity. | Mol Cancer Res | 2018 Oct |
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| 28 | 30015955 | Low‑frequency ultrasound and microbubbles combined with simvastatin promote the apoptosis of MCF‑7 cells by affecting the LATS1/YAP/RHAMM pathway. | Mol Med Rep | 2018 Sep |
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| 29 | 30106116 | Epigallocatechin-3-gallate affects the proliferation, apoptosis, migration and invasion of tongue squamous cell carcinoma through the hippo-TAZ signaling pathway. | Int J Mol Med | 2018 Nov |
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| 30 | 30250159 | PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein. | Cell Death Dis | 2018 Sep 24 |
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| 31 | 30366669 | FFAR1-and FFAR4-dependent activation of Hippo pathway mediates DHA-induced apoptosis of androgen-independent prostate cancer cells. | Biochem Biophys Res Commun | 2018 Nov 30 |
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| 32 | 30863499 | POPX2 is a novel LATS phosphatase that regulates the Hippo pathway. | Oncotarget | 2019 Feb 19 |
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| 33 | 30918126 | BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling. | Proc Natl Acad Sci U S A | 2019 Apr 9 |
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| 34 | 30999669 | Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP. | Cells | 2019 Apr 17 |
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| 35 | 31253872 | Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. | Oncogene | 2019 Jul |
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| 36 | 31351048 | Mono (2-ethylhexyl) phthalate (MEHP) triggers the proliferation of hemangioma-derived endothelial cells via YAP signals. | Chem Biol Interact | 2019 Sep 25 |
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| 37 | 31380285 | The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib. | Front Oncol | 2019 |
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| 38 | 31396349 | Apatinib suppresses breast cancer cells proliferation and invasion via angiomotin inhibition. | Am J Transl Res | 2019 |
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| 39 | 31540262 | CRISPR Loss-of-Function Screen Identifies the Hippo Signaling Pathway as the Mediator of Regorafenib Efficacy in Hepatocellular Carcinoma. | Cancers (Basel) | 2019 Sep 13 |
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| 40 | 31547587 | Activating Hippo Pathway via Rassf1 by Ursolic Acid Suppresses the Tumorigenesis of Gastric Cancer. | Int J Mol Sci | 2019 Sep 23 |
2 |
| 41 | 31569999 | Gα<sub>13</sub>-mediated LATS1 down-regulation contributes to epithelial-mesenchymal transition in ovarian cancer. | FASEB J | 2019 Dec |
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| 42 | 31848340 | LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function. | Nat Commun | 2019 Dec 17 |
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| 43 | 31912905 | Neratinib degrades MST4 via autophagy that reduces membrane stiffness and is essential for the inactivation of PI3K, ERK1/2, and YAP/TAZ signaling. | J Cell Physiol | 2020 Nov |
3 |
| 44 | 31938312 | LATS1 inhibits metastasis and epithelial-mesenchymal transition in head and neck squamous cell carcinoma. | Int J Clin Exp Pathol | 2018 |
3 |
| 45 | 32015438 | LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. | Nat Cell Biol | 2020 Feb |
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| 46 | 32420069 | Expression of large tumour suppressor (LATS) kinases modulates chemotherapy response in advanced non-small cell lung cancer. | Transl Lung Cancer Res | 2020 Apr |
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| 47 | 32749848 | Knockdown of microRNA-103a-3p inhibits the malignancy of thyroid cancer cells through Hippo signaling pathway by upregulating LATS1. | Neoplasma | 2020 Nov |
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| 48 | 32791482 | Generation of a serine/threonine-protein kinase LATS1 gene-edited iPSC MUSIi012-A-3. | Stem Cell Res | 2020 Oct |
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| 49 | 32944618 | LATS1-Beclin1 mediates a non-canonical connection between the Hippo pathway and autophagy. | Mol Cell Oncol | 2020 |
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| 50 | 32945354 | Long non‑coding RNA FOXD2‑AS1 regulates the tumorigenesis and progression of breast cancer via the S100 calcium binding protein A1/Hippo signaling pathway. | Int J Mol Med | 2020 Oct |
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