tumor susceptibility 101 ; Homo sapiens






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1 11595185 Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 2001 Oct 5 1
2 11805336 Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function. Proc Natl Acad Sci U S A 2002 Jan 22 1
3 11916981 Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. J Cell Biol 2002 Apr 1 2
4 12006492 Structure and functional interactions of the Tsg101 UEV domain. EMBO J 2002 May 15 1
5 12802020 TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc Natl Acad Sci U S A 2003 Jun 24 3
6 12915533 Tsg101 control of human immunodeficiency virus type 1 Gag trafficking and release. J Virol 2003 Sep 3
7 13679614 Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. J Gen Virol 2003 Oct 1
8 15043208 HIV capsid assembly. Curr HIV Res 2003 Jan 1
9 15044860 Reversal of multidrug resistance of gastric cancer cells by downregulation of TSG101 with TSG101siRNA. Cancer Biol Ther 2004 Jun 5
10 15053872 Ubiquitin recognition by the human TSG101 protein. Mol Cell 2004 Mar 26 3
11 15126635 Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding. J Cell Sci 2004 May 1 4
12 15163754 Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release. J Virol 2004 Jun 1
13 15197357 Pharmacogenomics on gastric cancer. Cancer Biol Ther 2004 Jun 2
14 15731271 The C-terminal half of TSG101 blocks Rous sarcoma virus budding and sequesters Gag into unique nonendosomal structures. J Virol 2005 Mar 1
15 15795524 Gag-p6 Tsg101 binding site duplications in maternal-infant HIV infection. AIDS Res Hum Retroviruses 2005 Mar 1
16 16004603 The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B. Biochem J 2005 Nov 1 2
17 16552148 Structure of human TSG101 UEV domain. Acta Crystallogr D Biol Crystallogr 2006 Apr 3
18 17048869 Hydrazone- and hydrazide-containing N-substituted glycines as peptoid surrogates for expedited library synthesis: application to the preparation of Tsg101-directed HIV-1 budding antagonists. Org Lett 2006 Oct 26 3
19 17182674 The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production. J Virol 2007 Mar 3
20 17229889 Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Mol Biol Cell 2007 Apr 3
21 17321722 A PKC-Sp1 signaling pathway induces early differentiation of human keratinocytes through upregulation of TSG101. Cell Signal 2007 Jun 8
22 17428861 Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site. J Virol 2007 Jun 1
23 18077552 Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase. Mol Biol Cell 2008 Feb 1
24 18083557 Protected aminooxyprolines for expedited library synthesis: application to Tsg101-directed proline-oxime containing peptides. Bioorg Med Chem Lett 2008 Feb 1 2
25 18643869 GISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation. J Neurochem 2008 Oct 1
26 18655064 SAR by oxime-containing peptide libraries: application to Tsg101 ligand optimization. Chembiochem 2008 Aug 11 1
27 19053244 Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol 2008 Dec 19 2
28 19210987 The TSG101 protein binds to connexins and is involved in connexin degradation. Exp Cell Res 2009 Apr 1 1
29 19244744 [The action of TSG101 on HIV-1 budding and related inhibitors]. Yao Xue Xue Bao 2008 Dec 2
30 19542561 Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions. Mol Cell Proteomics 2009 Nov 2
31 19914066 Application of ring-closing metathesis macrocyclization to the development of Tsg101-binding antagonists. Bioorg Med Chem Lett 2010 Jan 1 3
32 20004458 Ubiquitination of tombusvirus p33 replication protein plays a role in virus replication and binding to the host Vps23p ESCRT protein. Virology 2010 Feb 20 2
33 20399684 Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. Immunity 2010 Apr 23 1
34 20929444 Decoding the intrinsic mechanism that prohibits ALIX interaction with ESCRT and viral proteins. Biochem J 2010 Dec 15 4
35 21117030 Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway. Histol Histopathol 2011 Jan 1
36 21118645 [Expression and significance of TSG101, P21 and P300/CBP in squamous cell carcinoma and adenocarcinoma of the lung]. Zhongguo Fei Ai Za Zhi 2007 Jun 20 1
37 21643473 Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands. ACS Med Chem Lett 2011 May 12 2
38 21875593 ESCRT machinery potentiates HIV-1 utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) signaling cascade. J Mol Biol 2011 Oct 21 1
39 22102845 Bimolecular Complementation to Visualize Filovirus VP40-Host Complexes in Live Mammalian Cells: Toward the Identification of Budding Inhibitors. Adv Virol 2011 Jan 1 1
40 22438540 The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release. J Virol 2012 May 2
41 23104469 Culture systems for hepatitis E virus. J Gastroenterol 2013 Feb 4
42 23816704 Identification of α-taxilin as an essential factor for the life cycle of hepatitis B virus. J Hepatol 2013 Nov 1
43 24904548 Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly. Front Microbiol 2014 2
44 25682864 Biomolecular characterization of exosomes released from cancer stem cells: Possible implications for biomarker and treatment of cancer. Oncotarget 2015 Feb 20 3
45 26608825 TSG101, a tumor susceptibility gene, bidirectionally modulates cell invasion through regulating MMP-9 mRNA expression. BMC Cancer 2015 Nov 25 2
46 27280284 The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding. PLoS Pathog 2016 Jun 1
47 27648839 HIV-1 Vpr Abrogates the Effect of TSG101 Overexpression to Support Virus Release. PLoS One 2016 8
48 27856401 ESCRT-I Component VPS23A Affects ABA Signaling by Recognizing ABA Receptors for Endosomal Degradation. Mol Plant 2016 Dec 5 1
49 29571744 The NC domain of HIV-1 Gag contributes to the interaction of Gag with TSG101. Biochim Biophys Acta Gen Subj 2018 Jun 7
50 29859188 TSG101 interacts with the androgen receptor and attenuates its expression through the endosome/lysosome pathway. Biochem Biophys Res Commun 2018 Sep 3 2