DEAD-box helicase 3 X-linked ; Homo sapiens






93 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 8399 The pH dependence of binding of alpha,alpha'-dibromo-p-xylenesulfonic acid to lysozyme. Int J Pept Protein Res 1976 1
2 10074132 Hepatitis C virus core protein interacts with cellular putative RNA helicase. J Virol 1999 Apr 1
3 15507209 Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function. Cell 2004 Oct 29 1
4 17357160 Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity. Proteins 2007 Jun 1 3
5 17401195 Expression, purification, crystallization and preliminary X-ray diffraction analysis of the DDX3 RNA helicase domain. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 Apr 1 1
6 17631897 Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP. J Mol Biol 2007 Sep 7 15
7 18264132 Oncogenic role of DDX3 in breast cancer biogenesis. Oncogene 2008 Jun 26 2
8 18680273 Ring expanded nucleoside analogues inhibit RNA helicase and intracellular human immunodeficiency virus type 1 replication. J Med Chem 2008 Aug 28 1
9 18691757 Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells. Leuk Res 2009 Feb 1
10 19297497 DDX3 DEAD-Box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into nucleocapsids. J Virol 2009 Jun 1
11 19913487 Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure 2009 Nov 11 3
12 21237216 The role of DDX3 in regulating Snail. Biochim Biophys Acta 2011 Mar 5
13 21589879 A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication. PLoS One 2011 May 12 1
14 21698775 Toward the discovery of novel anti-HIV drugs. Second-generation inhibitors of the cellular ATPase DDX3 with improved anti-HIV activity: synthesis, structure-activity relationship analysis, cytotoxicity studies, and target validation. ChemMedChem 2011 Aug 1 3
15 21709606 Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation. Transplantation 2011 Aug 15 1
16 21904380 MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML. Leukemia 2012 Mar 2
17 22034099 The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export. J Cell Biochem 2012 Mar 7
18 22270009 Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III: Characterization of DDX3X as a target of S-adenosylmethionine. J Proteomics 2012 Jun 6 1
19 23290252 Structure-based drug design and potent anti-cancer activity of tricyclic 5:7:5-fused diimidazo[4,5-d:4',5'-f][1,3]diazepines. Bioorg Med Chem 2013 Feb 1 2
20 23410059 Low/negative expression of DDX3 might predict poor prognosis in non-smoker patients with oral cancer. Oral Dis 2014 Jan 1
21 23470959 DDX3 regulates DNA damage-induced apoptosis and p53 stabilization. Biochim Biophys Acta 2013 Jun 9
22 23478265 Human DEAD box helicase 3 couples IκB kinase ε to interferon regulatory factor 3 activation. Mol Cell Biol 2013 May 4
23 23659451 Multitargeting and antimetastatic potentials of silibinin in human HepG-2 and PLC/PRF/5 hepatoma cells. Nutr Cancer 2013 1
24 23974721 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells. Cancer Immunol Immunother 2013 Oct 5
25 24180280 Stimulation of DDX3 expression by ginsenoside Rg3 through the Akt/p53 pathway activates the innate immune response via TBK1/IKKε/IRF3 signalling. Curr Med Chem 2014 1
26 24183723 DDX3 RNA helicase is required for HIV-1 Tat function. Biochem Biophys Res Commun 2013 Nov 22 1
27 24461293 Dual inhibition of HCV and HIV by ring-expanded nucleosides containing the 5:7-fused imidazo[4,5-e][1,3]diazepine ring system. In vitro results and implications. Bioorg Med Chem Lett 2014 Feb 15 2
28 24748754 In-Vitro and in-Silico characterization of Sophora interrupta plant extract as an anticancer activity. Bioinformation 2014 8
29 25231298 DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level. J Virol 2014 Dec 2
30 25918862 Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer. Sci Rep 2015 Apr 28 9
31 26174373 RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity. Rev Med Virol 2015 Sep 2
32 26294807 The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas. Dis Markers 2015 1
33 26311743 Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer. Oncotarget 2015 Sep 29 1
34 26337079 NZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3. Oncotarget 2015 Oct 6 6
35 26584857 Inquiry of the electron density transfers in chemical reactions: a complete reaction path for the denitrogenation process of 2,3-diazabicyclo[2.2.1]hept-2-ene derivatives. Phys Chem Chem Phys 2015 Dec 28 3
36 26598523 Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. J Biol Chem 2016 Jan 29 2
37 26892600 DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis. Sci Rep 2016 Feb 19 2
38 27007150 DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis. Oncotarget 2016 Apr 19 2
39 27186411 Multifunctional DDX3: dual roles in various cancer development and its related signaling pathways. Am J Cancer Res 2016 1
40 27400883 The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer. BMC Cancer 2016 Jul 11 1
41 27634756 RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3. Cancer Res 2016 Nov 1 2
42 27735940 DDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania. Cell Death Dis 2016 Oct 13 9
43 27736973 The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription. PLoS One 2016 1
44 28128295 RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP. Sci Rep 2017 Jan 27 1
45 28246464 In vitro anti-cancer activity of doxorubicin against human RNA helicase, DDX3. Bioinformation 2016 14
46 28250386 Proteome Changes Induced by Imatinib and Novel Imatinib Derivatives in K562 Human Chronic Myeloid Leukemia Cells. Proteomes 2014 Jul 22 1
47 28402257 (DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit. Oncotarget 2017 May 16 2
48 28414160 Paraquat induces extrinsic pathway of apoptosis in A549 cells by induction of DR5 and repression of anti-apoptotic proteins, DDX3 and GSK3 expression. Toxicol In Vitro 2017 Aug 6
49 28435452 The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in <i>KRAS</i>-wild-type colorectal cancer. Theranostics 2017 1
50 28869602 Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment. Oncogene 2018 Jan 4 1