Title : Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity.

Pub. Date : 2007 Jun 1

PMID : 17357160






3 Functional Relationships(s)
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Protein Name
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1 Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity. Nucleosides DEAD-box helicase 3 X-linked Homo sapiens
2 We show that hDDX3 ATPase activity is stimulated by various ribo- and deoxynucleic acids. ribo- and deoxynucleic acids DEAD-box helicase 3 X-linked Homo sapiens
3 Comparative analysis with different nucleoside triphosphate analogs showed that the hDDX3 ATPase couples high catalytic efficiency to a rather relaxed substrate specificity, both in terms of base selection and sugar selection. [[(2R,3S,4R,5S)-3,4-dihydroxy-5-methyloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate DEAD-box helicase 3 X-linked Homo sapiens