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5 |
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6 |
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2 |
| 4 | 10873595 | Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. | Biochem Biophys Res Commun | 2000 Jun 24 |
1 |
| 5 | 11134001 | Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. | J Biol Chem | 2001 Mar 30 |
7 |
| 6 | 11159893 | Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. | Gastroenterology | 2001 Feb |
2 |
| 7 | 11356905 | Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. | J Pharmacol Exp Ther | 2001 Jun |
1 |
| 8 | 11477075 | Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. | J Biol Chem | 2001 Sep 21 |
6 |
| 9 | 11483603 | Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha. | J Biol Chem | 2001 Oct 5 |
4 |
| 10 | 11683238 | Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C. | Pharm Res | 2001 Sep |
8 |
| 11 | 11748225 | Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). | J Biol Chem | 2002 Feb 22 |
7 |
| 12 | 11826283 | Bile salt transporters. | Annu Rev Physiol | 2002 |
2 |
| 13 | 12085361 | Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver. | Hepatology | 2002 Jul |
2 |
| 14 | 12130747 | Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis. | J Pharmacol Exp Ther | 2002 Aug |
1 |
| 15 | 12196548 | A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter. | J Biol Chem | 2002 Nov 8 |
2 |
| 16 | 12490595 | Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation. | J Pharmacol Exp Ther | 2003 Jan |
2 |
| 17 | 12538813 | Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A. | J Pharmacol Exp Ther | 2003 Feb |
3 |
| 18 | 12568656 | Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin. | Biochem J | 2003 May 1 |
1 |
| 19 | 12601360 | Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression. | Hepatology | 2003 Mar |
4 |
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6 |
| 21 | 12763363 | Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. | J Hepatol | 2003 Jun |
2 |
| 22 | 12811365 | Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. | Clin Pharmacol Ther | 2003 Jun |
6 |
| 23 | 12906759 | Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin. | J Pharm Pharmacol | 2003 Jul |
3 |
| 24 | 12963436 | Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver. | Hepatol Res | 2003 Aug |
1 |
| 25 | 14530907 | Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins. | Naunyn Schmiedebergs Arch Pharmacol | 2003 Nov |
15 |
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2 |
| 27 | 14705859 | Pathophysiological factors affecting CAR gene expression. | Drug Metab Rev | 2003 Nov |
1 |
| 28 | 14977862 | Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity. | Drug Metab Dispos | 2004 Mar |
4 |
| 29 | 15096102 | Pharmacokinetics of flunixin in the cat: enterohepatic circulation and active transport mechanism in the liver. | J Vet Pharmacol Ther | 2004 Apr |
2 |
| 30 | 15116054 | Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. | Clin Pharmacol Ther | 2004 May |
4 |
| 31 | 15116058 | The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. | Clin Pharmacol Ther | 2004 May |
6 |
| 32 | 15159445 | Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. | J Pharmacol Exp Ther | 2004 Oct |
10 |
| 33 | 15194707 | Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. | J Pharmacol Exp Ther | 2004 Oct |
25 |
| 34 | 15226675 | High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1). | Pharmacogenetics | 2004 Jul |
4 |
| 35 | 15238259 | Identification of phalloidin uptake systems of rat and human liver. | Biochim Biophys Acta | 2004 Jul 1 |
2 |
| 36 | 15280219 | Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154. | Drug Metab Dispos | 2004 Nov |
6 |
| 37 | 15289793 | Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine. | Clin Pharmacol Ther | 2004 Aug |
8 |
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4 |
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2 |
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2 |
| 41 | 15467183 | New aspects of the blood-brain barrier transporters; its physiological roles in the central nervous system. | Biol Pharm Bull | 2004 Oct |
1 |
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1 |
| 43 | 15535988 | Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia. | Chem Biol Interact | 2004 Nov 20 |
3 |
| 44 | 15608127 | Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. | Drug Metab Dispos | 2005 Mar |
19 |
| 45 | 15652233 | Directional trans-epithelial transport of organic anions in porcine LLC-PK1 cells that co-express human OATP1B1 (OATP-C) and MRP2. | Biochem Pharmacol | 2005 Feb 1 |
3 |
| 46 | 15670600 | Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis. | J Mol Biol | 2005 Feb 18 |
1 |
| 47 | 15681900 | A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy. | Drug Metab Pharmacokinet | 2004 Dec |
4 |
| 48 | 15716364 | Hepatic uptake of the novel antifungal agent caspofungin. | Drug Metab Dispos | 2005 May |
5 |
| 49 | 15841457 | Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis. | Hepatology | 2005 May |
2 |
| 50 | 15842561 | Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1). | Br J Clin Pharmacol | 2005 May |
2 |