| 1 | 7743202 | A role of sigma receptors on hypoxia/hypoglycemia-induced decrease in CA1 presynaptic fiber spikes in rat hippocampal slices. | Brain Res | 1995 Jan 30 |
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| 2 | 8858982 | Enhancement of acetylcholine release by SA4503, a novel sigma 1 receptor agonist, in the rat brain. | J Pharmacol Exp Ther | 1996 Oct |
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| 3 | 8894608 | Sigma 1 receptor subtype is involved in the relief of behavioral despair in the mouse forced swimming test. | Eur J Pharmacol | 1996 Oct 3 |
2 |
| 4 | 9035256 | Reduction of the scopolamine-induced impairment of passive-avoidance performance by sigma receptor agonist in mice. | Physiol Behav | 1997 Feb |
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| 5 | 9188767 | In vivo regulation of serotonin 5-HT2A receptors in rat brain by subchronic administration of sigma receptor ligand NE-100. | Life Sci | 1997 |
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| 6 | 9544798 | Effect of SA4503, a novel sigma1 receptor agonist, against glutamate neurotoxicity in cultured rat retinal neurons. | Eur J Pharmacol | 1998 Jan 19 |
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| 7 | 9596556 | Activation of sigma1 receptor subtype leads to neuroprotection in the rat primary neuronal cultures. | Neurochem Int | 1998 Apr |
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| 8 | 9754932 | Sigma receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats. | Eur J Pharmacol | 1998 Aug 14 |
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| 9 | 9768559 | Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioral despair in mice exposed to tail suspension. | Pharmacol Biochem Behav | 1998 Nov |
2 |
| 10 | 10385231 | The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites. | Br J Pharmacol | 1999 May |
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| 11 | 10854906 | Effects of sigma(1) receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats. | Neuropharmacology | 2000 Jul 10 |
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| 12 | 10974323 | Effects of sigma receptor agonists on the impairment of spontaneous alternation behavior and decrease of cyclic GMP level induced by nitric oxide synthase inhibitors in mice. | Neuropharmacology | 2000 Sep |
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| 13 | 12485954 | Differences in cytochrome P450 forms involved in the metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a novel sigma ligand, in human liver and intestine. | Drug Metab Dispos | 2003 Jan |
14 |
| 14 | 15499608 | Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampus. | Synapse | 2005 Jan |
1 |
| 15 | 15618733 | Metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenyl-ethoxy)-phenyl]-ethyl-amine-monohydrochloride (NE-100), a novel sigma ligand: contribution of cytochrome P450 forms involved in the formation of individual metabolites in human liver and small intestine. | Drug Metab Pharmacokinet | 2003 |
4 |
| 16 | 15672756 | Prediction of differences in in vivo oral clearance of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl] ethylamine monohydrochloride (NE-100) between extensive and poor metabolizers from in vitro metabolic data in human liver microsomes lacking CYP2D6 activity and recombinant CYPs. | Xenobiotica | 2004 Jul |
6 |
| 17 | 16192112 | Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models. | Xenobiotica | 2005 Jun |
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| 18 | 16364377 | Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma 1 (sigma1) receptor: optical imaging study in rat hippocampal slices. | Neuropharmacology | 2006 Mar |
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| 19 | 16495935 | Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors. | Neuropsychopharmacology | 2007 Mar |
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| 20 | 17556637 | Role of N-methyl-D-aspartate receptors in antidepressant-like effects of sigma 1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride (SA-4503) in olfactory bulbectomized rats. | J Pharmacol Exp Ther | 2007 Sep |
2 |
| 21 | 20722474 | Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions. | Expert Opin Ther Targets | 2010 Oct |
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| 22 | 20802134 | Sigma1-receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice. | Am J Physiol Heart Circ Physiol | 2010 Nov |
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| 23 | 21434925 | Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice. | J Neurochem | 2011 Jun |
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| 24 | 21844826 | Distinct cardioprotective effects of 17β-estradiol and dehydroepiandrosterone on pressure overload-induced hypertrophy in ovariectomized female rats. | Menopause | 2011 Dec |
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| 25 | 22293694 | [Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist]. | Yakugaku Zasshi | 2012 |
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| 26 | 23041155 | Imipramine protects mouse hippocampus against tunicamycin-induced cell death. | Eur J Pharmacol | 2012 Dec 5 |
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| 27 | 23298811 | Stimulation of σ1-receptor restores abnormal mitochondrial Ca²⁺ mobilization and ATP production following cardiac hypertrophy. | Biochim Biophys Acta | 2013 Apr |
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| 28 | 23593332 | Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice. | PLoS One | 2013 |
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| 29 | 23618865 | A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells. | Biochem Biophys Res Commun | 2013 May 17 |
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| 30 | 24490863 | The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors. | Br J Pharmacol | 2014 Feb |
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| 31 | 24508523 | Interaction of new antidepressants with sigma-1 receptor chaperones and their potentiation of neurite outgrowth in PC12 cells. | Eur J Pharmacol | 2014 Mar 15 |
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| 32 | 24709917 | Antidepressant fluvoxamine reduces cerebral infarct volume and ameliorates sensorimotor dysfunction in experimental stroke. | Neuroreport | 2014 Jul 9 |
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| 33 | 25069239 | Involvement of sigma 1 receptor in the SSRI-induced suppression of the methamphetamine-induced behavioral sensitization and rewarding effects in mice. | Nihon Shinkei Seishin Yakurigaku Zasshi | 2013 Apr |
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| 34 | 26119915 | Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation. | Brain Res | 2015 Oct 5 |
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| 35 | 28389336 | The activity of selective sigma-1 receptor ligands in seizure models in vivo. | Behav Brain Res | 2017 Jun 15 |
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| 36 | 28815595 | Sigma-1 receptor ligands inhibit catecholamine secretion from adrenal chromaffin cells due to block of nicotinic acetylcholine receptors. | J Neurochem | 2017 Oct |
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| 37 | 29129596 | Amyloid toxicity is enhanced after pharmacological or genetic invalidation of the σ<sub>1</sub> receptor. | Behav Brain Res | 2018 Feb 26 |
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| 38 | 30543144 | Effects of fluvoxamine on nerve growth factor-induced neurite outgrowth inhibition by dexamethasone in PC12 cells. | Biosci Biotechnol Biochem | 2019 Apr |
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| 39 | 30557385 | Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors. | PLoS One | 2018 |
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| 40 | 31108174 | Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor. | Neurobiol Dis | 2019 Sep |
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| 41 | 33488945 | Stimulation of Sigma-1 Receptor Protects against Cardiac Fibrosis by Alleviating IRE1 Pathway and Autophagy Impairment. | Oxid Med Cell Longev | 2021 |
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