germacrone






26 Article(s)
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1 21497161 Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis. Eur J Pharmacol 2011 Sep 30 4
2 23117090 Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis. Eur J Pharmacol 2013 Jan 5 5
3 23771657 Germacrone induces apoptosis in human hepatoma HepG2 cells through inhibition of the JAK2/STAT3 signalling pathway. J Huazhong Univ Sci Technolog Med Sci 2013 Jun 17
4 23850985 Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system. Toxicol In Vitro 2013 Sep 5
5 24889088 Germacrone inhibits the proliferation of glioma cells by promoting apoptosis and inducing cell cycle arrest. Mol Med Rep 2014 Aug 7
6 25289068 Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells. Exp Ther Med 2014 Nov 6
7 25399081 The effects of germacrone on lipopolysaccharide-induced acute lung injury in neonatal rats. Cell Mol Biol (Noisy-le-grand) 2014 Nov 16 6
8 27573551 Germacrone Inhibits Estrogen Receptor α-Mediated Transcription in MCF-7 Breast Cancer Cells. Phytother Res 2016 Dec 4
9 27917474 Germacrone inhibits adipogenesis and stimulates lipolysis via the AMP-activated protein kinase signalling pathway in 3T3-L1 preadipocytes. J Pharm Pharmacol 2017 Feb 7
10 29218943 [Effect of germacrone in alleviating HUVECs damaged by H2O2-induced oxidative stress]. Zhongguo Zhong Yao Za Zhi 2017 Sep 8
11 29655913 Germacrone reverses adriamycin resistance in human chronic myelogenous leukemia K562/ADM cells by suppressing MDR1 gene/P-glycoprotein expression. Chem Biol Interact 2018 May 25 8
12 31318092 Germacrone attenuates cerebral ischemia/reperfusion injury in rats via antioxidative and antiapoptotic mechanisms. J Cell Biochem 2019 Nov 3
13 31451221 Germacrone alleviates collagen-induced arthritis via regulating Th1/Th2 balance and NF-κB activation. Biochem Biophys Res Commun 2019 Oct 20 3
14 31602228 Germacrone cooperates with dexmedetomidine to alleviate high-fat diet-induced type 2 diabetes mellitus via upregulating AMPKα1 expression. Exp Ther Med 2019 Nov 2
15 32020876 Germacrone exerts anti-cancer effects on gastric cancer through induction of cell cycle arrest and promotion of apoptosis. BMC Complement Med Ther 2020 Jan 23 5
16 32071920 Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells. Biomed Res Int 2020 14
17 32145743 Germacrone protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy processes in PC12 cells. BMC Complement Med Ther 2020 Mar 7 10
18 32547235 Germacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells. Cancer Manag Res 2020 4
19 33010370 Inhibitory activities of curzerenone, curdione, furanodienone, curcumol and germacrone on Ca<sup>2+</sup>-activated chloride channels. Fitoterapia 2020 Nov 1
20 33132314 Germacrone Reduces Cisplatin-Induced Toxicity of Renal Proximal Tubular Cells via Inhibition of Organic Cation Transporter. Biol Pharm Bull 2020 5
21 33244453 Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells. Front Oncol 2020 3
22 33402180 Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress. BMC Complement Med Ther 2021 Jan 5 2
23 33835632 Germacrone improves liver fibrosis by regulating the PI3K/AKT/mTOR signalling pathway. Cell Biol Int 2021 Sep 20
24 33880579 Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway. Mol Med Rep 2021 Jun 10
25 34847832 miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury. Bioengineered 2022 Jan 2
26 35156515 Germacrone alleviates okadaic acid-induced neurotoxicity in PC12 cells via M1 muscarinic receptor-mediated Galphaq (Gq)/phospholipase C beta (PLCβ)/ protein kinase C (PKC) signaling. Bioengineered 2022 Mar 1