benzyloxycarbonylleucyl-leucyl-leucine aldehyde






2221 Article(s)
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1 8694836 Enhancement of CPP32-like activity in the TNF-treated U937 cells by the proteasome inhibitors. Biochem Biophys Res Commun 1996 Jul 5 3
2 9030516 Proteasome- and p53-dependent masking of signal transducer and activator of transcription (STAT) factors. J Biol Chem 1997 Feb 21 2
3 9133543 Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines. Diabetes 1997 May 1
4 9162019 Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation. J Biol Chem 1997 May 30 2
5 9186501 Calpain contributes to silica-induced I kappa B-alpha degradation and nuclear factor-kappa B activation. Arch Biochem Biophys 1997 Jun 15 2
6 9266962 Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin. Oncogene 1997 Aug 14 24
7 9278421 Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 1997 Sep 5 1
8 9286755 Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo. J Bone Miner Res 1997 Sep 1
9 9367633 Degradation of connexin43 gap junctions involves both the proteasome and the lysosome. Exp Cell Res 1997 Nov 1 2
10 9438391 mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway. Cell Growth Differ 1998 Jan 8
11 9497367 Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem 1998 Mar 13 4
12 9506962 Proteolytic regulation of the zinc finger transcription factor YY1, a repressor of muscle-restricted gene expression. J Biol Chem 1998 Mar 20 2
13 9529323 Yersinia enterocolitica impairs activation of transcription factor NF-kappaB: involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor alpha production. J Exp Med 1998 Apr 6 4
14 9535733 Effects of proteasomal inhibitors on the maturation of the insulin proreceptor: an anatomical paradox. Biochem Biophys Res Commun 1998 Mar 27 1
15 9568691 Evidence for involvement of the proteasome complex (26S) and NFkappaB in IL-1beta-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells. Diabetes 1998 Apr 4
16 9572490 Epidermal growth factor activation of NF-kappaB is mediated through IkappaBalpha degradation and intracellular free calcium. Oncogene 1998 Apr 23 3
17 9573251 The major component of IkappaBalpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells. J Virol 1998 Jun 3
18 9598838 Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells. Arterioscler Thromb Vasc Biol 1998 May 1
19 9620666 Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants. J Leukoc Biol 1998 Jun 1
20 9653139 Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway. Proc Natl Acad Sci U S A 1998 Jul 7 1
21 9657527 Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha. FASEB J 1998 Jul 2
22 9679971 Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance. Cancer Res 1998 Jul 15 1
23 9698598 Inhibition of TNF-alpha-induced NF-kappaB activation and IL-8 release in A549 cells with the proteasome inhibitor MG-132. Am J Respir Cell Mol Biol 1998 Aug 4
24 9710593 Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway. Mol Cell Biol 1998 Sep 1
25 9722548 Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2. J Biol Chem 1998 Sep 4 8
26 9737957 c-Fos degradation by the proteasome. An early, Bcl-2-regulated step in apoptosis. J Biol Chem 1998 Sep 25 2
27 9786937 Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand. J Biol Chem 1998 Oct 30 1
28 9831079 Proteasome-mediated degradation of the vitamin D receptor (VDR) and a putative role for SUG1 interaction with the AF-2 domain of VDR. J Cell Biochem 1998 Dec 1 2
29 9836745 Cell cycle -dependent proteolysis in plants. Identification Of the destruction box pathway and metaphase arrest produced by the proteasome inhibitor mg132 Plant Cell 1998 Dec 1
30 9887050 Differential monocyte adhesion and adhesion molecule expression in venous and arterial endothelial cells. Am J Physiol 1999 Jan 1
31 9892011 Termination of growth hormone pulse-induced STAT5b signaling. Mol Endocrinol 1999 Jan 3
32 9920768 Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression. Biochem Biophys Res Commun 1999 Jan 8 9
33 9931444 Ubiquitin-proteasome-dependent degradation of apolipoprotein B100 in vitro. Biochim Biophys Acta 1999 Jan 29 1
34 9933632 NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro. J Biol Chem 1999 Feb 12 3
35 9950608 Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor. Invest Ophthalmol Vis Sci 1999 Feb 3
36 9973252 Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation. Mol Endocrinol 1999 Feb 5
37 10023669 Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins. Oncogene 1999 Jan 28 2
38 10037479 Activation of stress-activated protein kinases correlates with neurite outgrowth induced by protease inhibition in PC12 cells. J Neurochem 1999 Mar 4
39 10051559 Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A 1999 Mar 2 3
40 10075698 Osmotic response element is required for the induction of aldose reductase by tumor necrosis factor-alpha. J Biol Chem 1999 Mar 19 2
41 10095055 Characterization and expression of the mouse Hsc70 gene. Biochim Biophys Acta 1999 Mar 19 1
42 10096573 Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription. Cancer Res 1999 Mar 15 1
43 10209066 Ciliary neurotrophic factor and phorbol ester each decrease selected STAT3 pools in neuroblastoma cells by proteasome-dependent mechanisms. Cytokine 1999 Mar 2
44 10212182 p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor beta1. J Biol Chem 1999 Apr 30 1
45 10226064 Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants. Am J Respir Cell Mol Biol 1999 May 1
46 10229115 Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia. J Neuroimmunol 1999 Mar 1 3
47 10229667 Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. Biochem J 1999 May 15 7
48 10347228 Characterization of the translation-dependent step during iron-regulated decay of transferrin receptor mRNA. J Biol Chem 1999 Jun 4 2
49 10415162 Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity. Mol Med 1999 Jun 1
50 10433212 Intracellular signaling in rat cultured vascular smooth muscle cells: roles of nuclear factor-kappaB and p38 mitogen-activated protein kinase on tumor necrosis factor-alpha production. Endocrinology 1999 Aug 2