Bortezomib






2135 Article(s)
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2101 35205670 Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma. Cancers (Basel) 2022 Feb 12 1
2102 35213543 Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice. PLoS One 2022 2
2103 35218967 Cellular membrane-based vesicles displaying a reconstructed B cell maturation antigen for multiple myeloma therapy by dual targeting APRIL and BAFF. Acta Biomater 2022 Apr 15 4
2104 35236820 NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma. Cell Death Dis 2022 Mar 2 7
2105 35238869 The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells. Invest Ophthalmol Vis Sci 2022 Mar 2 1
2106 35242236 Transient receptor potential channels in multiple myeloma. Oncol Lett 2022 Apr 2
2107 35278160 Metformin Relieves Bortezomib-Induced Neuropathic Pain by Regulating AMPKa2-Mediated Autophagy in the Spinal Dorsal Horn. Neurochem Res 2022 Jul 17
2108 35291602 Effect of Proteasome Inhibitor on Vascular Cell Adhesion Molecule-1 (VCAM-1) and Intercellular Adhesion Molecule-1 (ICAM-1) Expressions in Rat Model of Atherosclerosis. Rep Biochem Mol Biol 2022 Jan 6
2109 35294057 Solamargine induces autophagy-mediated apoptosis and enhances bortezomib activity in multiple myeloma. Clin Exp Pharmacol Physiol 2022 Jun 2
2110 35307764 Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer. Mol Biomed 2022 Mar 21 1
2111 35315341 System Xc<sup>-</sup> inhibition blocks bone marrow-multiple myeloma exosomal crosstalk, thereby countering bortezomib resistance. Cancer Lett 2022 Jun 1 2
2112 35321428 Caspase-8: Friend or Foe in Bortezomib/Lenalidomide-Based Therapy for Myeloma. Front Oncol 2022 4
2113 35326742 Targeting an MDM2/MYC Axis to Overcome Drug Resistance in Multiple Myeloma. Cancers (Basel) 2022 Mar 21 4
2114 35344764 Indirubin-3'-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma. EBioMedicine 2022 Apr 2
2115 35352576 Bortezomib-Induced Ovarian Toxicity in Mice. Toxicol Pathol 2022 Apr 2
2116 35389552 Posttranslational modification of Aurora A-NSD2 loop contributes to drug resistance in t(4;14) multiple myeloma. Clin Transl Med 2022 Apr 5
2117 35394126 (-)-Epigallocatechin-3-gallate plays an antagonistic role in the antitumor effect of bortezomib in myeloma cells via activating Wnt/β-catenin signaling pathway. Adv Clin Exp Med 2022 Apr 8 4
2118 35397613 ΔNp63α promotes Bortezomib resistance via the CYGB-ROS axis in head and neck squamous cell carcinoma. Cell Death Dis 2022 Apr 9 2
2119 35409095 Specific Attenuation of Purinergic Signaling during Bortezomib-Induced Peripheral Neuropathy In Vitro. Int J Mol Sci 2022 Mar 29 1
2120 35434028 Bortezomib-containing regiment in treating glomerulopathy with fibronectin deposits combined with monoclonal gammopathy of undetermined significance: a case report and literature review. Ann Transl Med 2022 Mar 2
2121 35443750 The BCL-2 inhibitor ABT-199/venetoclax synergizes with proteasome inhibition via transactivation of the MCL-1 antagonist NOXA. Cell Death Discov 2022 Apr 20 1
2122 35453452 TLR4 Signaling and Heme Oxygenase-1/Carbon Monoxide Pathway Crosstalk Induces Resiliency of Myeloma Plasma Cells to Bortezomib Treatment. Antioxidants (Basel) 2022 Apr 12 19
2123 35453623 Proteasome Inhibitors Decrease the Viability of Pulmonary Arterial Smooth Muscle Cells by Restoring Mitofusin-2 Expression under Hypoxic Conditions. Biomedicines 2022 Apr 9 3
2124 35462913 SHP2 Inhibitors Show Anti-Myeloma Activity and Synergize With Bortezomib in the Treatment of Multiple Myeloma. Front Pharmacol 2022 5
2125 35467582 Combination Therapy of an Antibody Specific for Transferrin Receptor 1 (ch128.1/IgG1) With Bortezomib or Lenalidomide Results in Increased Survival in an In Vivo Model of Human Multiple Myeloma: A Brief Communication. J Immunother 2022 Jun 1 2
2126 35508865 PLK4 inhibitor plus bortezomib exhibits a synergistic effect on treating multiple myeloma via inactivating PI3K/AKT signaling. Ir J Med Sci 2022 May 4 5
2127 35524959 Bortezomib inhibits the proteasome, leading to cell death via apoptosis in feline injection site sarcoma cells in vitro. Am J Vet Res 2022 May 8 2
2128 35547772 Enhanced ASGR2 by microplastic exposure leads to resistance to therapy in gastric cancer. Theranostics 2022 1
2129 35568791 Heme-regulated inhibitor: an overlooked eIF2α kinase in cancer investigations. Med Oncol 2022 May 15 2
2130 35577689 Multifunctional liposomal nanostructure-mediated siRNA/bortezomib co-delivery for SHARP1 knockdown in MLL-AF6 acute myeloid leukemia. Mater Sci Eng C Mater Biol Appl 2022 Jan 26 9
2131 35579277 HDL-mediated reduction of cholesterol content inhibits the proliferation of prostate cancer cells induced by LDL: Role of ABCA1 and proteasome inhibition. Biofactors 2022 May 1
2132 35589686 The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma. Cell Death Dis 2022 May 19 8
2133 35596703 Functional characterization and clinical significance of super-enhancers in lung adenocarcinoma. Mol Carcinog 2022 May 21 1
2134 35604822 A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. Mol Cancer Res 2022 May 23 10
2135 35637111 TRPA1 promotes melanosome phagocytosis in keratinocytes via PAR-2/CYLD axis. J Dermatol Sci 2022 Jun 4