N-Acetyl-L-cysteine






44 Article(s)
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1 9258275 Antioxidant inhibition of protein kinase C-signaled increases in transforming growth factor-beta in mesangial cells. Metabolism 1997 Aug 1
2 11477102 A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways. J Biol Chem 2001 Oct 5 1
3 12387820 Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells. Biochem Biophys Res Commun 2002 Oct 25 1
4 14757367 Serum amyloid A-induced mRNA expression and release of tumor necrosis factor-alpha (TNF-alpha) in human neutrophils. Immunol Lett 2004 Jan 30 2
5 15093752 The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib. Exp Cell Res 2004 May 1 2
6 15240725 TNF-induced beta2 integrin activation involves Src kinases and a redox-regulated activation of p38 MAPK. J Immunol 2004 Jul 15 2
7 15530848 Reactive oxygen species mediate RANK signaling in osteoclasts. Exp Cell Res 2004 Dec 10 3
8 15604259 Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res 2004 Dec 15 2
9 15680482 Angiotensin II suppresses growth arrest specific homeobox (Gax) expression via redox-sensitive mitogen-activated protein kinase (MAPK). Regul Pept 2005 Apr 15 1
10 15860230 Regulation of IL-18 expression by CRH in mouse microglial cells. Immunol Lett 2005 May 15 3
11 16036107 Cas IIgly induces apoptosis in glioma C6 cells in vitro and in vivo through caspase-dependent and caspase-independent mechanisms. Neoplasia 2005 Jun 1
12 16445087 Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium. Environ Toxicol Chem 2005 Dec 3
13 16553631 Secretion of brain-derived neurotrophic factor from brain microvascular endothelial cells. Eur J Neurosci 2006 Mar 1
14 17014914 IL-18 enhances the migration ability of murine melanoma cells through the generation of ROI and the MAPK pathway. Immunol Lett 2006 Nov 15 2
15 17371789 Oral N-acetyl-L-cysteine is a safe and effective precursor of cysteine. J Anim Sci 2007 Jul 1
16 17389234 Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP. J Cell Biol 2007 Mar 26 1
17 18097021 Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells. J Immunol 2008 Jan 1 1
18 19028451 Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells. Biochem Biophys Res Commun 2009 Jan 16 2
19 19062520 [Changes in matrix metalloproteinases activities in normal and transformed mouse fibroblasts under effect of antioxidants]. Tsitologiia 2008 2
20 19641517 Oxidation of cell surface thiol groups by contact sensitizers triggers the maturation of dendritic cells. J Invest Dermatol 2010 Jan 1
21 20090884 Cadmium increases ferroportin-1 gene expression in J774 macrophage cells via the production of reactive oxygen species. Nutr Res Pract 2009 Fall 1
22 20876761 Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am J Physiol Endocrinol Metab 2010 Dec 2
23 21311680 Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT116 Human Colon Cancer Cells; Involvement of Reactive Oxygen Species. Korean J Physiol Pharmacol 2010 Dec 2
24 21461234 Involvement of ROS in Curcumin-induced Autophagic Cell Death. Korean J Physiol Pharmacol 2011 Feb 2
25 21567078 Up-regulation of Foxo4 mediated by hepatitis B virus X protein confers resistance to oxidative stress-induced cell death. Int J Mol Med 2011 Aug 1
26 21600945 Cigarette smoke-induced kinin B1 receptor promotes NADPH oxidase activity in cultured human alveolar epithelial cells. Peptides 2011 Jul 1
27 21711425 Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis. Hepatol Res 2011 Jul 1
28 22546375 Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling. Toxicol Lett 2012 Jun 20 1
29 22771329 Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells. Biochem Biophys Res Commun 2012 Aug 3 3
30 22995899 Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. Blood 2012 Dec 13 2
31 24349491 Mitochondrial DNA damage via augmented oxidative stress regulates endoplasmic reticulum stress and autophagy: crosstalk, links and signaling. PLoS One 2013 1
32 24403080 Redox control of human mitochondrial outer membrane protein MitoNEET [2Fe-2S] clusters by biological thiols and hydrogen peroxide. J Biol Chem 2014 Feb 14 1
33 24796846 LRP1-dependent pepsin clearance induced by 2'-hydroxycinnamaldehyde attenuates breast cancer cell invasion. Int J Biochem Cell Biol 2014 Aug 2
34 24987341 Activation of mGluR2/3 underlies the effects of N-acetylcystein on amygdala-associated autism-like phenotypes in a valproate-induced rat model of autism. Front Behav Neurosci 2014 1
35 25119188 Suberoylanilide hydroxamic acid induces ROS-mediated cleavage of HSP90 in leukemia cells. Cell Stress Chaperones 2015 Jan 1
36 25578230 The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264.7 cells. Toxicol Lett 2015 Mar 4 1
37 26391887 Signaling Mechanisms in the Nitric Oxide Donor- and Amphetamine-Induced Dopamine Release in Mesencephalic Primary Cultured Neurons. Neurotox Res 2016 Jan 1
38 26535918 NADPH Oxidase-Dependent Mechanism Explains How Arsenic and Other Oxidants Can Activate Aryl Hydrocarbon Receptor Signaling. Chem Res Toxicol 2015 Dec 21 1
39 27677689 Bortezomib Enhances the Antitumor Effects of Interferon-β Gene Transfer on Melanoma Cells. Anticancer Agents Med Chem 2017 1
40 28388573 αMSH prevents ROS-induced apoptosis by inhibiting Foxo1/mTORC2 in mice adipose tissue. Oncotarget 2017 Jun 20 1
41 29163689 Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells. Oncol Lett 2017 Dec 4
42 29407091 Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes. Int J Cardiol 2018 Mar 1 1
43 31837563 AMPK/p38/Nrf2 activation as a protective feedback to restrain oxidative stress and inflammation in microglia stimulated with sodium fluoride. Chemosphere 2020 Apr 2
44 32788068 ROS/p38MAPK-induced lamin B1 accumulation promotes chronic kidney disease-associated vascular smooth muscle cells senescence. Biochem Biophys Res Commun 2020 Oct 15 1