Title : Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells.

Pub. Date : 2012 Dec 13

PMID : 22995899






2 Functional Relationships(s)
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1 Finally, we demonstrate that the effect of Meis1 knockout on HSCs is entirely mediated through reactive oxygen species where treatment of the Meis1 knockout mice with the scavenger N-acetylcystein restored HSC quiescence and rescued HSC function. N-Acetyl-L-cysteine Meis homeobox 1 Mus musculus
2 Finally, we demonstrate that the effect of Meis1 knockout on HSCs is entirely mediated through reactive oxygen species where treatment of the Meis1 knockout mice with the scavenger N-acetylcystein restored HSC quiescence and rescued HSC function. N-Acetyl-L-cysteine Meis homeobox 1 Mus musculus