2,4-Diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline






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1 11980916 Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. J Cell Biol 2002 Apr 29 9
2 15004235 The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins. Mol Biol Cell 2004 May 11
3 15047703 The binary interacting network of the conserved oligomeric Golgi tethering complex. J Biol Chem 2004 Jun 4 18
4 15728195 Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells. J Cell Biol 2005 Feb 28 1
5 15932880 Cog1p plays a central role in the organization of the yeast conserved oligomeric Golgi complex. J Biol Chem 2005 Jul 29 2
6 16020545 Subunit architecture of the conserved oligomeric Golgi complex. J Biol Chem 2005 Sep 23 4
7 16051600 Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. J Biol Chem 2005 Sep 23 5
8 16354716 The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans. Development 2006 Jan 5
9 16420527 COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation. Traffic 2006 Feb 1
10 16895472 C. elegans as a model system to study the function of the COG complex in animal development. Biol Chem 2006 Aug 1
11 17220172 A new inborn error of glycosylation due to a Cog8 deficiency reveals a critical role for the Cog1-Cog8 interaction in COG complex formation. Hum Mol Genet 2007 Apr 1 3
12 17565980 Structural analysis of conserved oligomeric Golgi complex subunit 2. J Biol Chem 2007 Aug 10 1
13 18086915 Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability. J Cell Biol 2007 Dec 17 3
14 19536132 Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing. EMBO J 2009 Jul 22 1
15 20633274 Comparative analyses of the Conserved Oligomeric Golgi (COG) complex in vertebrates. BMC Evol Biol 2010 Jul 15 3
16 20874812 Interaction of Golgin-84 with the COG complex mediates the intra-Golgi retrograde transport. Traffic 2010 Dec 8
17 20972446 Molecular organization of the COG vesicle tethering complex. Nat Struct Mol Biol 2010 Nov 2
18 21421995 Conserved oligomeric Golgi complex specifically regulates the maintenance of Golgi glycosylation machinery. Glycobiology 2011 Dec 3
19 21807881 The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport. J Cell Biol 2011 Aug 8 1
20 23057818 COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity. Traffic 2013 Feb 4
21 23462996 COG complexes form spatial landmarks for distinct SNARE complexes. Nat Commun 2013 6
22 23865579 Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes. Traffic 2013 Oct 2
23 24806965 TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport. J Cell Sci 2014 Jul 1 2
24 25331899 Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. Proc Natl Acad Sci U S A 2014 Nov 4 1
25 26260076 Key features and clinical variability of COG6-CDG. Mol Genet Metab 2015 Nov 1
26 26578865 Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function. Front Neurosci 2015 1
27 27174018 Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites. Xenobiotica 2017 Mar 4
28 27259349 Alterations in blood pressure, antioxidant status and caspase 8 expression in cobalt chloride-induced cardio-renal dysfunction are reversed by Ocimum gratissimum and gallic acid in Wistar rats. J Trace Elem Med Biol 2016 Jul 1
29 27385402 COG lobe B sub-complex engages v-SNARE GS15 and functions via regulated interaction with lobe A sub-complex. Sci Rep 2016 Jul 7 3
30 27481842 The role of acroblast formation during Drosophila spermatogenesis. Biol Open 2016 Aug 15 1
31 28659916 HLA-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared to HLA-Bw4-T-80 and HLA-A-Bw4 Isoforms in Rituximab or Dinutuximab-Based Cancer Immunotherapy. Front Immunol 2017 4
32 28794270 The Golgin protein Coy1 functions in intra-Golgi retrograde transport and interacts with the COG complex and Golgi SNAREs. Mol Biol Cell 2017 Aug 9 3
33 28883096 COG7 deficiency in <i>Drosophila</i> generates multifaceted developmental, behavioral and protein glycosylation phenotypes. J Cell Sci 2017 Nov 1 3
34 29573151 More than just sugars: Conserved oligomeric Golgi complex deficiency causes glycosylation-independent cellular defects. Traffic 2018 Jun 1
35 31073031 Conserved juxtamembrane domains in the yeast golgin Coy1 drive assembly of a megadalton-sized complex and mediate binding to tethering and SNARE proteins. J Biol Chem 2019 Jun 21 2
36 33394555 Disorder of sex development associated with a novel homozygous nonsense mutation in COG6 expands the phenotypic spectrum of COG6-CDG. Am J Med Genet A 2021 Apr 2
37 34603392 Development and Initial Characterization of Cellular Models for COG Complex-Related CDG-II Diseases. Front Genet 2021 3
38 35578731 Hydrogen Recovery from Coke Oven Gas. Comparative Analysis of Technical Alternatives. Ind Eng Chem Res 2022 May 11 1