Title : Conserved juxtamembrane domains in the yeast golgin Coy1 drive assembly of a megadalton-sized complex and mediate binding to tethering and SNARE proteins.

Pub. Date : 2019 Jun 21

PMID : 31073031






2 Functional Relationships(s)
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1 We found that this conserved region is necessary and sufficient for binding the SNARE protein Sed5 and the COG complex. 2,4-Diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline t-SNARE syntaxin Saccharomyces cerevisiae S288C
2 We propose that Coy1 assembles into a docking platform that directs COG-bound vesicles toward cognate SNAREs on the Golgi membrane. 2,4-Diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline Coy1p Saccharomyces cerevisiae S288C