Methionine Sulfoximine






131 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 24637 Differential inhibition of glutamine and gamma-glutamylcysteine synthetases by alpha-alkyl analogs of methionine sulfoximine that induce convulsions. J Biol Chem 1978 Apr 10 4
2 241345 Evidence for methionine sulfoximine as a transition-state analog for glutamine synthetase from NMR and EPR data. Biochem Biophys Res Commun 1975 Oct 6 1
3 1194915 In vivo inhibition of gamma-glutamylcysteine synthetase by L-methionine-RS-sulfoximine; influence on intermediates of the gamma-glutamyl cycle. J Neurochem 1975 Nov 1
4 1353787 Effect of pH on glutamine content derived from exogenous glutamate in astrocytes. J Neurochem 1992 Sep 1
5 1479587 ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors. J Med Chem 1992 Dec 25 1
6 1677585 What the clinician can learn from MR glutamine/glutamate assays. NMR Biomed 1991 Apr 1
7 1678150 Variations in the effects of L-methionine-DL-sulfoximine on the activity of cerebral gamma-glutamyl transpeptidase in rats as a function of age. Neurosci Lett 1991 May 13 2
8 1681554 Methionine sulfoximine intensifies cancer anorexia. Pharmacol Biochem Behav 1991 May 1
9 1982483 Glutamine synthetase inhibition prevents cerebral oedema during hyperammonemia. Acta Neurochir Suppl (Wien) 1990 1
10 2305410 Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion. Stroke 1990 Feb 1
11 2565645 Astrocytic pathology of methionine sulfoximine-induced encephalopathy. Acta Neuropathol 1989 2
12 2566651 Role of glial cells for the basal and Ca2+-dependent K+-evoked release of transmitter amino acids investigated by microdialysis. J Neurochem 1989 Jun 1
13 2567236 Functional hepatocyte heterogeneity. Vascular 2-oxoglutarate is almost exclusively taken up by perivenous, glutamine-synthetase-containing hepatocytes. Eur J Biochem 1989 May 15 1
14 2571428 Pharmacologic modulation of increased release of gluconeogenic precursors from extra-splanchnic organs in sepsis. Circ Shock 1989 Sep 1
15 2573391 Simultaneous synthesis and degradation of glutamine in isolated rat liver cells. Effect of vasopressin. Biochim Biophys Acta 1989 Nov 20 1
16 2757524 DNA synthesis in Alzheimer type II astrocytosis. The question of astrocytic proliferation and mitosis in experimentally induced hepatic encephalopathy. Arch Neurol 1989 Aug 1
17 2862950 The effect of methioninesulfoximine, an inhibitor of glutamine synthetase, on the levels of amino acids in the intact and decorticated rat neostriatum. Brain Res 1985 Jul 8 1
18 2862994 Influence of glutamine on the growth of human glioma and medulloblastoma in culture. Cancer Res 1985 Sep 1
19 2875229 Metabolism and transport of amino acids studied by immunocytochemistry. Med Biol 1986 1
20 2884208 Cloning and characterization of Saccharomyces cerevisiae genes that confer L-methionine sulfoximine and tabtoxin resistance. J Bacteriol 1987 Jun 2
21 2904726 Age-dependent variation in the sensitivity of rat brain glutamine synthetase to L-methionine-DL-sulfoximine. Int J Dev Neurosci 1988 3
22 2906283 Effects of varying doses of methionine sulfoximine on liver glutamine synthetase activity and time courses of blood and urinary nitrogenous compounds in the chicken (Gallus domesticus). Comp Biochem Physiol B 1988 3
23 2916664 Effect of acute metabolic acidosis on ammonia metabolism in kidney. Am J Physiol 1989 Feb 2
24 3011827 Glycogen synthesis and immunocytochemical study of fructose-1,6-biphosphatase in methionine sulfoximine epileptogenic rodent brain. J Cereb Blood Flow Metab 1986 Jun 3
25 3326731 Urea cycle disorders, hyperammonemia and neurotransmitter changes. Enzyme 1987 2
26 3816789 Urea synthesis from ammonia in periportal and pericentral regions of the liver lobule. Effect of oxygen. Eur J Biochem 1987 Feb 16 1
27 4308004 Inhibition of glutamine synthetase by methionine sulfoximine. Studies on methionine sulfoximine phosphate. Biochemistry 1969 Jun 1
28 4393740 Identification of L-methionine-S-sulfoximine as the convulsant isomer of methionine sulfoximine. Proc Natl Acad Sci U S A 1970 Jun 2
29 5242120 Phosphorylation of methionine sulfoximine by glutamine synthetase. Proc Natl Acad Sci U S A 1968 Jan 1
30 5911550 The inhibition of cerebral glutamine synthetase by structural analogs of the convulsant dl-methionine sulfoximine. Biochem Pharmacol 1966 Mar 1
31 6105150 Repression of nitrate reductase in Neurospora studied by using L-methionine-DL-sulfoximine and glutamine auxotroph gln-1b. J Bacteriol 1980 Jul 1
32 6129977 Ammonia uptake by skeletal muscle in the hyperammonaemic rat. Eur J Clin Invest 1982 Dec 1
33 6137246 [Mechanism of inhibition of pea chloroplast glutamine synthetase by methionine sulfoximine]. Biokhimiia 1983 Jul 1
34 6140923 Effects of methionine sulfoximine on the enzymes of glutamate metabolism in isolated astrocytes of rat brain. Biochem Pharmacol 1983 Dec 15 3
35 6142510 Renal recovery from metabolic acidosis in the rat: no role for glutamine synthetase. Ren Physiol 1984 1
36 6149260 Alteration of striatal glutamate release after glutamine synthetase inhibition. J Neurochem 1984 Nov 1
37 6259295 Stimulation of fructose-1,6-biphosphatase activity and synthesis in the cerebral cortex of rats submitted to the convulsant methionine sulfoximine. J Neurochem 1981 Mar 6
38 6414814 Hepatocyte heterogeneity in glutamate uptake by isolated perfused rat liver. Eur J Biochem 1983 Nov 2 1
39 6421997 Induction of brain ornithine decarboxylase during recovery from metabolic, mechanical, thermal, or chemical injury. J Neurochem 1984 Apr 1
40 6795864 Effect of methionine sulfoximine (MSO) on the regional activity of choline acetyltransferase in rat brain. Zentralbl Veterinarmed A 1981 2
41 6852039 Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur J Biochem 1983 Jun 15 1
42 7012853 Transport of neutral amino acids at the blood-brain barrier. Pharmacology 1981 1
43 7116136 Ammonia and methionine sulfoximine intoxication. Brain Res 1982 Jun 24 2
44 7526622 Astrocyte swelling in liver failure: role of glutamine and benzodiazepines. Acta Neurochir Suppl (Wien) 1994 1
45 7674372 Hyperammonemia increases serotonin 1A receptor expression in both rat hippocampus and a transfected hippocampal cell line, HN2-5. J Neurosci Res 1995 May 1 1
46 7910378 Kinetic, ESR, and trapping evidence for in vivo binding of Mn(II) to glutamine synthetase in brain cells. Neurochem Res 1994 Feb 2
47 8188174 Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis. Hepatology 1994 Jun 1
48 8436955 Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy. J Neurochem 1993 Mar 1
49 8614939 Impaired pial arteriolar reactivity to hypercapnia during hyperammonemia depends on glutamine synthesis. Stroke 1996 Apr 3
50 8813413 Inhibition of glutamine synthetase activity prevents memory consolidation. Brain Res Cogn Brain Res 1996 Jul 1