Title : Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression.

Pub. Date : 1999 Feb

PMID : 9929500






2 Functional Relationships(s)
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1 Liver and intestinal microsomes that contained an equal or greater amount of CYP3A5, in addition to CYP3A4, were less susceptible to inhibition by both ketoconazole and fluconazole. Ketoconazole cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 Liver and intestinal microsomes that contained an equal or greater amount of CYP3A5, in addition to CYP3A4, were less susceptible to inhibition by both ketoconazole and fluconazole. Fluconazole cytochrome P450 family 3 subfamily A member 5 Homo sapiens