Title : The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.

Pub. Date : 1998 Dec 15

PMID : 9865719






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 PTEN encodes a phosphatase that recognizes phosphoprotein substrates and the phospholipid, phosphatidylinositol-3,4,5-triphosphate. Phospholipids phosphatase and tensin homolog Homo sapiens
2 PTEN encodes a phosphatase that recognizes phosphoprotein substrates and the phospholipid, phosphatidylinositol-3,4,5-triphosphate. phosphatidylinositol 3,4,5-triphosphate phosphatase and tensin homolog Homo sapiens
3 Akt/protein kinase B, a gene whose antiapoptotic function is regulated by phosphatidylinositol-3,4,5-triphosphate, was able to rescue cells from PTEN-dependent death. phosphatidylinositol 3,4,5-triphosphate phosphatase and tensin homolog Homo sapiens