Pub. Date : 1998 Nov 13
PMID : 9849882
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Selective involvement of caspase-3 in ceramide induced apoptosis in AK-5 tumor cells. | Ceramides | caspase 3 | Rattus norvegicus |
| 2 | The present study demonstrates the activation of caspase-3/CPP-32beta, during apoptosis induced by cell permeable exogenous ceramides, in AK-5 tumor, a spontaneously regressing rat histiocytoma. | Ceramides | caspase 3 | Rattus norvegicus |
| 3 | The present study demonstrates the activation of caspase-3/CPP-32beta, during apoptosis induced by cell permeable exogenous ceramides, in AK-5 tumor, a spontaneously regressing rat histiocytoma. | Ceramides | caspase 3 | Rattus norvegicus |
| 4 | The apoptotic events were suppressed by the caspase-3 specific tetrapeptide inhibitor DEVD-CHO but not by the caspase-1 inhibitor YVAD-CMK. | aspartyl-glutamyl-valyl-aspartal | caspase 3 | Rattus norvegicus |
| 5 | Furthermore the processing of caspase-3 to its active form upon apoptotic stimulus, and the subsequent cleavage of the substrate PARP, suggested a central role for caspase-3 in the ceramide mediated apoptosis in AK-5 tumor cells. | Ceramides | caspase 3 | Rattus norvegicus |
| 6 | Furthermore the processing of caspase-3 to its active form upon apoptotic stimulus, and the subsequent cleavage of the substrate PARP, suggested a central role for caspase-3 in the ceramide mediated apoptosis in AK-5 tumor cells. | Ceramides | caspase 3 | Rattus norvegicus |