Title : Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.

Pub. Date : 1998 Sep 24

PMID : 9748363






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These substituted dihydroxynaphthoic acids are selective inhibitors of human lactate dehydrogenase-H (LDH-H) and LDH-M and of lactate dehydrogenase from the malarial parasite Plasmodium falciparum (pLDH). dihydroxynaphthoic acids lactate dehydrogenase A Homo sapiens
2 Selectivity for LDH-H, LDH-M, or pLDH is strongly dependent upon the groups that are in the 4- and 7-positions of the dihydroxynaphthoic acid backbone. 2,3-dihydroxynaphthalene-1-carboxylic acid lactate dehydrogenase A Homo sapiens