Protein Name lactate dehydrogenase A
Organism Homo sapiens
Gene ID 3939
Gene Symbol

LDHA

UniProt P00338 (LDHA_HUMAN), V9HWB9 (V9HWB9_HUMAN)
Relationships Total Number of functionally related compound(s) : 275
Total Number of Articles : 431
Description

lactate dehydrogenase A

Gene Summary

This gene encodes the A subunit of lactate dehydrogenase enzyme which catalyzes the reversible conversion of pyruvate to lactate with the concomitant oxidation of NADH to NAD in anaerobic glycolysis. The protein is found predominantly in skeletal muscle and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2023]

synonyms
  • L-lactate dehydrogenase A chain
  • LDH muscle subunit
  • LDH-A
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Properties