Title : Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

Pub. Date : 1998 Sep

PMID : 9710629






1 Functional Relationships(s)
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1 In the present series of studies, the short-chain ceramide analog C2-ceramide inhibited insulin-stimulated glucose transport by approximately 50% in 3T3-L1 adipocytes, with similar reductions in hormone-stimulated translocation of the insulin-responsive glucose transporter (GLUT4) and insulin-responsive aminopeptidase. N-acetylsphingosine leucyl and cystinyl aminopeptidase Homo sapiens