Protein Name leucyl and cystinyl aminopeptidase
Organism Homo sapiens
Gene ID 4012
Gene Symbol


Relationships Total Number of functionally related compound(s) : 127
Total Number of Articles : 116

leucyl and cystinyl aminopeptidase

Gene Summary

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

  • leucyl-cystinyl aminopeptidase
  • AT (4) receptor
  • angiotensin IV receptor
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