| Protein Name | leucyl and cystinyl aminopeptidase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4012 |
| Gene Symbol | LNPEP |
| UniProt | Q9UIQ6 (LCAP_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
127
Total Number of Articles : 116 |
Description |
leucyl and cystinyl aminopeptidase |
| Gene Summary |
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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| Properties | |